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刘兴国
单位:生命科学学院
地址:广州市科学城开源大道190号
邮编:510530
电话:86-20-32015225
个人主页: http://stemlab.gibh.ac.cn/web/stemlab/lxg
实验室介绍:
 
个人简历 Personal resume
获得国家自然科学“优秀青年”基金,广东省科技创新“领军人才”,首届广东省自然科学杰出青年基金,首届广东省科技创新“青年拔尖人才”,国际生物物理学会评为“2011 Young Bioenergeticist Award”(每年只有一人获此奖项)。刘兴国研究员以第一作者或通讯作者在国际杂志上发表18余篇论文(影响因子累计超过105),单篇最高他引超过130次,多篇获得F1000推荐,其中,唯一通讯作者在Cell Metabolism、Hepatology等杂志发表7篇。论文被Cell,Science等多个顶级杂志广泛引用。申请专利9项,其中1项为PCT国际专利。现任8个国际学术杂志编委。10次受邀在国际学术大会上进行大会特邀报告。主持973计划(课题负责人),国家自然科学基金(4项),中科院战略性先导项目,广东省对外合作项目(合作者为苏国辉院士),广州市科技计划等多项基金。
 
研究方向 Research direction
1、细胞命运调控的亚细胞水平机制
2、线粒体生物学
 
招生信息 Enrollment information
  
 
论文专著 The monograph
1) Transient activation of mitoflashes modulates Nanog at the early phase of somatic cell reprogramming - Cell Metabolism - 2016 - 2016年第1期
2) Valproic acid‐induced hepatotoxicity in alpers syndrome is associated with mitochondrial permeability transition pore opening‐dependent apoptotic sensitivity in an induced pluripotent stem cell model - Hepatology - 2015 - 2015第5期
3) FRAP screening identifies Gadd45a as a heterochromatin relaxer that enhances iPSC generation - EMBO Reports - 2016 - 2016
4) Srebp‐1 Interacts with c‐Myc to Enhance Somatic Cell Reprogramming - Stem Cells - 2016 - 2016年第1期
5) Mitochondrial fusion provides an ‘initial metabolic complementation’ controlled by mtDNA - Cellular and Molecular Life Sciences - 2015 - 2015年第13期
6) Mitochondrial Membrane Potential-dependent Endoplasmic Reticulum Fragmentation is an Important Step in Neuritic Degeneration - CNS Neuroscience & Therapeutics - 2016 - 2016
7) Modeling of Mitochondrial Donut Formation - Biophysical Journal - 2015 - 2015第5期
8) Mitochondrial metabolism transition cooperates with nuclear reprogramming during induced pluripotent stem cell generation - Biochemical and Biophysical Research Communication - 2013 - 2013年第4期
9) Current approaches to reduce or eliminate mitochondrial DNA mutations. - Sci China Life Sci. - 2016 - 2016
10) Mitochondrial 'kiss-and-run': interplay between mitochondrial motility and fusion-fission dynamics - EMBO J - 2009 - 2009
11) Altered fusion dynamics underlie unique morphological changes in mitochondria during hypoxia-reoxygenation stress - Cell Death Differ - 2011 - 2011
12) Distribution and apoptotic function of outer membrane proteins depend on mitochondrial fusion - Mol Cell - 2014 - 2014
13) Ca2+-dependent regulation of mitochondrial dynamics by the Miro-Milton complex - Int J Biochem Cell Biol - 2009 - 2009
14) Biophysical properties of mitochondrial fusion events in pancreatic beta-cells and cardiac cells unravel potential control mechanisms of its selectivity - Am J Physiol Cell Physiol - 2010 - 2010
15) Sorbitol regulates energy transfer from allophycocyanin to the terminal emitter within phycobilisomes in Synechocystis - Biotechnol Lett - 2007 - 2007
16)  Biogenesis of chlorophyll-binding proteins under iron stress in Synechocystis - Biochemistry (Mosc) - 2006 - 2006
17)  Two-Component Signal Transduction Systems in the Cyanobacterium Synechocystis - Tsinghua Science & Technology - 2006 - 2006
18) Oxidative stress and metal ions effects on the cores of phycobilisomes in Synechocystis - FEBS Lett - 2005 - 2005
19) Purification and characterization of two small heat shock proteins from Anabaena - IUBMB Life - 2005 - 2005
 
报考意向 Ambition
 
 
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