1) Selectively Targeting FLT3-ITD Mutants Over FLT3-wt by a Novel Inhibitor for Acute Myeloid Leukemia - Haematologica - 202004 - 2021, 106(2):605-609.
2) Discovery of a highly potent and selective Bruton’s tyrosine kinase inhibitor avoiding impairment of ADCC effects for B-cell non-Hodgkin lymphoma - Signal Transduction and Targeted Therapy - 202009 - 2020, 5(1):200.
3) All-trans retinoic acid exerts selective anti-FLT3-ITD acute myeloid leukemia efficacy through downregulating Chk1 kinase - Cancer Letters - 202003 - 2020, 473:130-138.
4) Repurposing cabozantinib to GISTs: Overcoming multiple imatinib-resistant cKIT mutations including gatekeeper and activation loop mutants in GISTs preclinical models - Cancer Letters - 201901 - 2019, 447:105-114.
5) Discovery of a highly potent FLT3 kinase inhibitor for FLT3-ITD-positive AML - Leukemia - 201605 - 2016, 30
6) Ibrutinib selectively targets FLT3-ITD in mutant FLT3-positive AML - Leukemia - 201603 - 2016, 30
7) Discovery of a BTK/MNK Dual Inhibitor for Lymphoma and Leukemia - Leukemia - 201601 - 2016, 30
8) Discovery of 4-Methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl) phenyl)-3-((1-nicotinoylpiperidin-4-yl)oxy)benzamide (CHMFL-ABL/KIT-155) as a Novel Highly Potent 4 Type II ABL/KIT Dual Kinase Inhibitor with a Distinct Hinge Binding - J. Med. Chem. - 201701 - 2017, 60
9) Discovery of (R)-1-(3-(4-Amino-3-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one (CHMFL-EGFR-202) as a Novel Irreversible EGFR Mutants Kinase Inhibitor with a Distinct Binding Mode - J. Med. Chem. - 201704 - 2017, 60
10) Discovery of N(3-((1-Isonicotinoylpiperidin-4-yl)oxy)-4-methylphenyl)-3- (trifluoromethyl)benzamide (CHMFL-KIT-110) as a Selective Potent, and Orally Available Type II cKIT Kinase Inhibitor for Gastrointestinal Stromal Tumors (GISTs) - J. Med. Chem. - 201604 - 2016, 59
11) Discovery of (E)-N1-(3-Fluorophenyl)-N3-(3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)malonamide (CHMFL-KIT-033) as a Novel c-KIT T670I Mutant Selective Kinase Inhibitor for Gastrointestinal Stromal Tumors (GISTs) - JOURNAL OF MEDICINAL CHEMISTRY - - 0022-2623
12) Discovery of (E)-N1-(3-Fluorophenyl)-N3-(3-(2-(pyridin-2- yl)vinyl)-1H-indazol-6-yl)malonamide (CHMFL-KIT-033) as a Novel c-KIT T670I Mutant Selective Kinase Inhibitor for Gastrointestinal Stromal Tumors (GISTs) - JOURNAL OF MEDICINAL CHEMISTRY - - 0022-2623
13) Discovery of N-(4-(6-Acetamidopyrimidin-4-yloxy)phenyl)-2-(2- (trifluoromethyl)phenyl)acetamide (CHMFL-FLT3-335) as a Potent FMS-like Tyrosine Kinase 3 Internal Tandem Duplication (FLT3-ITD) Mutant Selective Inhibitor for Acute Myeloid Leukemia - JOURNAL OF MEDICINAL CHEMISTRY - - 0022-2623
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