访问量:4278
 
马宏伟
单位:中国科学院苏州纳米技术与纳米仿生研究所
地址:江苏省苏州工业园区若水路398号
邮编:215123
电话:0512-62872562
个人主页: http://sourcedb.sinano.cas.cn/zw/zjrck/200907/t20090722_2155836.html
实验室介绍:
 
个人简历 Personal resume
马宏伟,中国科学院研究员,博士生导师。1999年毕业于上海复旦大学化学系,2005年获得美国杜克大学生物医学工程系博士学位。2005年-2008年在北京大学工学院生物医学工程系任特聘研究员,博导。2008年至今在苏州纳米所工作,曾获2013年江苏省双创人才、2012年姑苏创业人才,2010年第四届苏州工业园区科技领军人才奖、2009年中国化学会青年化学奖、北京大学Exxon Mobil教学和科研奖等。
研究兴趣:自身免疫疾病的纳米诊断技术。主要学术成绩:发展了表面引发聚合反应的表面修饰新技术,解决了“蛋白质非特异性吸附”(NPA)这一共性难题,构筑了一系列功能化的生物界面,开发出系列产品,初步实现产业转化。近年来,出版国际专著一部,先后在Journal of the American Chemical Society、Advaced Materials、Small等期刊发表论文70余篇,被引用1000余次。拥有中国授权发明专利14项,美国授权发明专利3项,并已申请 17项国家发明专利。
 
研究方向 Research direction
1、自身免疫疾病的纳米诊断技术
2、免疫
3、生物界面
 
招生信息 Enrollment information
知识背景:需要物理化学或是细胞生物学方面的学习经历。
考试科目与学生待遇参照研究所统一标准。
 
论文专著 The monograph
1) Subcellular and Dynamic Coordination between Src Activity and Cell Protrusion in Microenvironment - Scientific Reports - 201508 - 5:12963
2) An ultralow background substrate for protein microarray technology - Analyst - 201606 - 140(16)
3) A quartz crystal microbalance as a tool for biomolecular interaction studies - RSC Adv. - 201507 - 5(79)
4) Chimeric peptide constructs comprising linear B-cell epitopes: application to the serodiagnosis of infectious diseases - Scientific Reports - 201508 - 5:13364
5) Autoantibodies to chromogranin A are potential diagnostic biomarkers for non-small cell lung cancer - Tumor Biol. - 201507 - 36(12)
6) iPDMS based microarray reveals relationship between non-specific interaction and irreproducibility - Anal Chem. - 201506 - 87(14)
7) Robust anti-reflective silica nanocoatings: abrasion resistance enhanced via capillary condensation of APTES - J. Mater. Chem. C - 201503 - 3(17)
8) Surface confined retro Diels-Alder reaction driven by the swelling of weak polyelectrolytes - ACS Appl. Mater. Inter. - 201503 - 7(11)
9) In Vitro Hemocompatibility and Toxic Mechanism of Graphene Oxide on Human Peripheral Blood T Lymphocytes and Serum Albumin - ACS Appl. Mater. Inter. - 201411 - 6(22)
10) Trend of telomerase activity change during human iPSC self-renewal and differentiation revealed by a quartz crystal microbalance based assay - Scientific Reports - 201411 - 4:6978
11) Interaction of graphene oxide with human serum albumin and its mechanism - RSC Adv. - 201410 - 4(98)
12) Molecular Composition, Grafting Density and Film Area Affect the Swelling-Induced Au-S Bond Breakage - ACS Appl. Mater. Inter. - 201406 - 6(11)
13) Long-term self-renewal of human pluripotent stem cells on peptide-decorated poly(OEGMA-co-HEMA) brushes under fully defined conditions - Acta Biomater. - 201307 - 9(11)
14) FRET imaging of calcium signaling in live cells in the microenvironment - Integr.Biol. - 201211 - 5(2)
15) Single-Step Rapid Assembly of DNA Origami Nanostructures for Addressable Nanoscale Bioreactors - J. Am. Chem. Soc. - 201212 - 135(2)
16) Label-Free Real-Time Detection of DNA Methylation Based on Quartz Crystal Microbalance Measurement - Anal. Chem. - 201301 - 85(4)
17) Simultaneous and rapid detection of multiple pesticide and veterinary drug residues by suspension array technology - Biosens.Bioelectron. - 201210 - 41(5)
18) A proton shelter inspired by the sugar coating of acidophilic archaea - Scientific Reports - 201211 - 2(48)
19) Single-chain polymers achieved from radical polymerization under single initiator conditions - Langmuir - 201210 - 28(42)
20) Poly(ionic liquid)-wrapped single-walled carbon nanotubes for sub-ppb detection of CO2 - Chem. Commun. - 201206 - 48(66)
21) Surface initiated polymerization from integrated poly(dimethylsiloxane) enables crack-free large area wrinkle formation - Polym.Adv. Technol. - 201108 - 23(9)
22) old nanoparticles-based nanoconjugates for enhanced enzyme cascade and glucose sensing - Analyst - 201208 - 137(19)
23) Solidified liquid layer model expands the application fields of quartz crystal microbalance - Macro. Rapid Commun. - 201205 - 33(9)
24) Unexpected Temperature-dependent Single Chain Mechanics of Poly(N-isopropyl-acrylamide) in Water - Langmuir - 201202 - 28(11)
25) Tunning the surface chemistry of iPDMS for improved protein microarray performance - J. Mater.Chem. - 201202 - 22(13)
26) The change in thickness of the solidified liquid layer rather than the immobilized mass determines the frequency response of a quartz crystal microbalance - SCI CHINA CHEM. - 201101 - 55(1)
27) Fibronectin and Bone Morphogenetic Protein-2-Decorated Poly(OEGMA-r-HEMA) Brushes Promote Osseointegration of Titanium Surfaces - Langmuir - 201109 - 27(19)
28) Predicting Au-S bonds breakage from the swelling behavior of surface tethered polyelectrolytes - Soft Matter - 201110 - 7(24)
29) Swelling induced Au-S bond breakage is determined by the molecular composition of surface tethered copolymers-carboxylated poly(OEGMA-r-HEMA) - Chem. Commun. - 201107 - 47(47)
30)  Solidified liquid layer model makes quartz crystal microbalance a convenient molecular ruler - Colloid Surface B. - 201106 - 85(1)
31) The use of micropatterning to control smooth muscle myosin heavy chain expression and limit the response to transforming growth factor β1 in vascular smooth muscle cells - Biomaterials - 201009 - 32(2)
32) Directly observed Au-S bond breakage due to swelling of the anchored polyelectrolyte - Chem. Commun. - 201011 - 47(4)
33) Poly(dimethylsiloxane) elastomers with tethered peptide ligands for cell adhesion studies - Acta Biomater. - 201002 - 6(8)
34) A quartz crystal microbalance-based molecular ruler for biopolymers - Chem. Commun. - 200912 - 46(6)
35) Optimization of evanescent wave imaging for the visualization of protein adsorption layers - SCI CHINA PHYS MECH. - 201008 - 53(10)
36) Surface initiated polymerization from substrates of low initiator density and its applications in biosensors - ACS Appl. Mater. Inter. - 201010 - 2(11)
37) A DNA-origami chip platform for label-free SNP genotyping using toehold-mediated strand displacement - Small - 201009 - 6(17)
38) A nanofibrous membrane with tunable surface chemistry: preparation and application in protein microarrays - J. Mater. Chem. - 201009 - 20(45)
39) Arranging junctions for nanofibers - Nanoscale - 200911 - 2(2)
40) Integrated poly(dimethysiloxane) with an intrinsic nonfouling property approaching “Absolute” zero background in immunoassays - Anal. Chem. - 201007 - 82(15)
41) Controlled wrinkle formation via bubble inflation strain engineering - Soft Matter - 201008 - 6(18)
42)  One-step fabrication of porous polymeric microcage via electrified jetting - Nanoscale - 201005 - 2(6)
43) Electrospinning of poly (dimethylsiloxane) nanofibrous membrane: fabrication and application in protein microarrays - Biomacromolecules - 200911 - 10(12)
44) Substrate induced controllable wrinkling for facile nanofabrication - Macromol. Rapid Commun. - 200907 - 30(18)
45)  Real-time measurement of the mass of water expelled by poly(N-isopropylacrylamide) brushes upon thermo-induced collapse - Chem. Commun. - 200904 - issue 23
46)  Convergence of dissipation and impedance analysis of quartz crystal microbalance studies - Anal. Chem. - 200812 - 81(2)
47) Photoelectric conversion switch based on quantum dots with i-motif DNA scaffolds - Chem. Commun. - 200903 - 17(17)
48) Quartz crystal microbalance study of the kinetics of surface initiated polymerization - Sci. China, Ser. B Chem. - 200912 - 52(12)
49) Surface-imprinted nanostructured layer-by-layer film for molecular recognition of theophylline derivatives - Langmuir - 200809 - 24(20)
50) Study viscoelasticity of ultra-thin poly(oligo(ethylene glycol) methacrylate) brushes by a quartz crystal microbalance with dissipation - Langmuir - 200805 - 24(12)
51) Investigation of the interactions between silver nanoparticles and hela cells by scanning electrochemicalmicroscopy - Analyst - 200807 - 133(9)
52) Superhydrophobic poly(dimethylsiloxane) via surface- initiated polymerization with ultralow initiator density - Macromolecules - 200808 - 41(18)
53) A facile method for permanent and functional surface modification of poly(dimethylsiloxane) - J. Am. Chem. Soc. - 200705 - 129(23)
54) Study and application of a linear frequency-thickness relation for surface initiated atom transfer radical polymerization in quartz crystal microbalance - Macromolecules - 200704 - 40(9)
55) Protein resistant polymer coatings on silicon oxide by surface initiated atom transfer radical polymerization - Langmuir - 200603 - 22(8)
56) Surface-initiated atom transfer radical polymerization of oligo(ethylene glycol) methyl methacrylatefrom mixed self-assembled monolayer on gold - Adv. Funct. Mater. - 200701 - 8(2)
57) Analysis of long range correlations due to coherent light scattering due from in vitro cell arrays using angle-resolved low coherence interferometry - J. Biomed. Opt. - 200606 - 11(3)
58) Monitoring kinetics of surface-initiated atom transfer radical polymerization by quartz crystal microbalance with dissipation - Biointerphases - 200603 - 1(1)
59) Pretreatment of amphiphilic comb polymer surfaces dramatically affects protein adsorption - Biomacromolecules - 200509 - 6(6)
60) Fabrication of biofunctionalized quasi-three-dimensional microstructures of a nonfouling comb polymer using soft lithography - Adv. Funct.Mater. - 200503 - 15(4)
61) Stimulus-responsive poly(N-isopropylacrylamide) brushes and nanopatterns prepared by Surface- Initiated Polymerization - Chem. Mater. - 200408 - 16(19)
62) “Non-fouling” oligo(ethylene glycol)-functionalized polymerbrushessynthesized by surface-initiated atom transfer radical polymerization - Adv. Mater. - 200402 - 16(4)
63) Surface engineering strategies for control of protein and cell interactions - Surf. Sci. - 200410 - 570(1-2)
64) Universal route to cell micropatterning using an amphiphilic comb polymer - Adv. Mater. - 200304 - 15(7-8)
65) Micropatterns of a cell-adhesive peptide on an amphiphilic comb polymer film - Langmuir - 200203 - 18(8)
66) Radical-mediated diastereoselective construction of a chiral synthon for synthesis of dolabellanes - Org. Lett. - 199908 - 1(5)
 
报考意向 Ambition
 
 
 

如果有意向报考此老师的硕士或博士,请留下你的信息。

 
  姓  名: 移动电话:
  电子邮箱: 所学专业:
  毕业院校: 报考类型: 博士 硕士
  国  别:
  个人照片: ( 支持格式:JPEG,JPG,PNG,GIF文件大小请勿超过1M)
 

个人简历:

( 支持格式:PDF,DOC,DOCX,JPG,JPEG,文件大小请勿超过1M)
  成 绩 单: ( 支持格式:PDF,DOC,DOCX,JPG,JPEG,文件大小请勿超过1M)
  备注:
(限150字)
 
   
         
         
         
 
COPYRIGHT 2007 中国科学技术大学研究生院、校学位办 All Rights Reserved 地址:安徽省合肥市金寨路96号 邮编:230026。
TEL:+86-551-63602928 FAX:+86-551-63602179 E-mail:gradschl@ustc.edu.cn