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汪劲
单位:中国科学院长春应用化学研究所电分析化学国家重点实验室
地址:吉林省长春市人民大街5625号
邮编:130022
电话:0431-85262003
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个人简历 Personal resume
中国科学院长春应用化学研究所,博士生导师。主要从事生物物理和化学、分析和计算、经典和量子非平衡态统计物理等领域研究。涉及分子识别、单分子动力学和生物网络等物理化学和生物学及环境科学交叉研究的前沿和热点。以第一或主要作者和通讯联系人在国际核心期刊上发表研究论文 汪劲教授以第一或主要作者和通讯联系人在国际核心期刊发表研究论文260多篇(1篇 Nature. Struct. Mol. Biol.,1篇 Advances in Physics , 17 篇 Proc. Natl. Acad. Sci. USA, 4篇 J. Am. Chem. Soc., 7篇 Phys. Rev. Lett. ,2篇Angew. Chem. Int. Ed., 3篇Chem. Sci, 1篇Nucleic Acids Res.等)。总引用6200多次, h-index 为42。会议特邀报告及相关学术报告200多次,其中多次在美国化学会年会、美国物理学会年会、美国Gorden Conference等重大国际会议上作邀请报告(2016年任美国Gorden Conference副主席,2017年任美国Gorden Conference主席)。已培养博士后、博士和硕士20多名。2003年获德国Baden-Wurttemberg奖励;2005年获美国国家自然科学基金生涯奖(Career Award);2010 年当选美国物理学会会士(Fellow)。2012年当选美国科学促进协会(AAAS, American Association for the Advancement of Science) 会士。2013年中-美化学和化学生物学教授协会授予优秀教授卓越成就奖。
 
研究方向 Research direction
1、生物物理与化学
2、计算生物物理化学
3、经典和量子非平衡态统计物理
 
招生信息 Enrollment information
具有生物、物理、化学、计算机等知识背景
 
论文专著 The monograph
1) A Cake-style CoS2@MoS2/RGO Hybrid Catalyst for Efficient Hydrogen Evolution. - Advanced Functional Material. - 2017 - 27(5), 1602699
2) Binding Mechanism and Dynamic Conformational Change of C subunit of Protein Kinase A with Different Pathways. - Proc. Natl. Acad. Sci. USA. - 2017 - 114(38): E7959-E7968
3) SPA-LN: a scoring function of ligand–nucleic acid interactions via optimizing both specificity and affinity. - Nucleic Acids Res. - 2017 - 45(12):e110
4) Molecular mechanism of multispecific recognition of Calmodulin through conformational changes . - Proc. Natl. Acad. Sci. USA. - 2017 - 114, E3927–E3934
5) Landscape and flux theory of non-equilibrium dynamical systems with application to biology - Advances in Physics - 2015 - 64:1, 1-137
6) Hybrid of gold nanostar and indocyanine green for targeted imaging-guided diagnosis and phototherapy using low-density laser irradiation. - J. Mater. Chem. B - 2016 - 4, 5842.
7) Universal statistical fluctuations in thermodynamics and kinetics of single molecular recognition. - Phys. Chem. Chem. Phys. - 2016 - 18, 8570-8578.
8) Scalable synthesis of Cu-based ultrathin nanowires networks and their electrocatalytic properties. - Nanoscale. - 2016 - 8, 4927-4932
9) A promising approach to molecular counting problem in super resolution microscopy. - Proc. Natl. Acad. Sci. USA. - 2015 - 112(2), 304-305
10) C.H. Li, J. Wang*. Landscape and flux reveal a new global view and physical quantification of mammalian cell cycle. Proc. Natl. Acad. Sci. USA. 111(39), 14130-14135 - - 2014 -
11) Y. Wang, S. Longhi, P. Roche , J. Wang*. Reply to Jensen and Blackledge: Dual quantifications of intrinsically disordered proteins by NMR ensembles and molecular dynamics simulations. Proc. Natl. Acad. Sci. USA. 111, E1559-E1559 - - 2014 -
12) H. Yan, L. Zhao, L. Hu, X. Wang, E.K. Wang, J. Wang*. Nonequilibrium landscape theory of neural networks. Proc. Natl. Acad. Sci. USA E4185-E4194 - - 2013 -
13) K. Zhang, M. Sasai, J. Wang*. Eddy current and coupled landscapes for nonadiabatic, nonequilibrium dynamics of complex systems. Proc. Natl. Acad. Sci. USA 110, 14930-14935 - - 2013 -
14) Y. Wang, X.K. Chu, W. Han, E.K. Wang, J. Wang*. Multiscaled exploration of coupled folding and binding of an intrinsically disordered molecular recognition element in measles virus nucleoprotein . Proc. Natl. Acad. Sci. USA 110 , E3743-E3752 - - 2013 -
15) X.K. Chu, L.F. Gan, E.K. Wang, J. Wang*.Quantifying the topography of the intrinsic energy landscape of flexible biomolecular recognition. Proc. Natl. Acad. Sci. USA, 110(26):2342-2351 - - 2013 -
16)  X. Yang, L.F. Gan, L. Han, E.K. Wang, J. Wang*. High-Yield Synthesis of Silver Nanoclusters Protected by DNA Monomers and DFT Prediction of their Photoluminescence Properties. Angew. Chem. Int. Ed. 52, 2202-2206. - - 2013 -
17) Z. Hensel, H. Feng, B. Han, C. Hatem, J. Wang*, J. Xiao, Stochastic expression dynamics of transcription factor revealed by single-molecule noise analysis. Nature. Struct. Mol. Biol. 19,797-802 .Journal Cover Page Article. - - 2012 -
18) Y. Wang, X.K. Chu, Z.C. Suo, E.K. Wang, J. Wang*, Multidomain Protein Solves the Folding Problem by Multifunnel Combined Landscape: Theoretical Investigation of a Y-Family DNA Polymerase. J. Am. Chem. Soc., 134, 13755-13764 - - 2012 -
19) J. Wang*, R. J., Oliveira, X.K. Chu, P.C. Whitford, J. Chahine, H. Wei, E.K. Wang, J. N. Onuchic, V. B.P. Leite, Topography of funneled landscapes determines thethermodynamics and kinetics of protein folding. Proc. Natl. Acad. Sci. USA, 109, 15763-8 - - 2012 -
20) J. Wang*, K. Zhang, L. Xu, E.K. Wang, Quantifying the Waddington landscape and biological paths for development and differentiation. Proc. Natl. Acad. Sci. USA 108, 8257-8262 - - 2011 -
21) J. Wang*, C.H. Li, and E.K. Wang, Potential and flux landscapes quantify the stability and robustness of budding yeast cell cycle network. Proc. Natl. Acad. Sci. USA 107, 8195-8200 - - 2010 -
22)  J. Wang*, "Cellular and Biomolecular Recognition: Synthetic and Non-Biological Molecules". J. Am. Chem. Soc. 132, 6611 - - 2010 -
23) J. Wang*, C.H. Li, E. K. Wang, X.D. Wang, Uncovering the rules for protein-protein interactions from yeast genomic data. Proc. Natl. Acad. Sci. USA 106, 3752-3757 - - 2009 -
24) J. Wang*, L. Xu, E. K. Wang, Potential Landscape and Flux Framework of Non-Equilibrium Networks: Robustness, Dissipation and Coherence of Biochemical Oscillations. Proc. Natl. Acad. Sci. USA 105, 12271-12276 - - 2008 -
25) S. Lapidus, B. Han, J. Wang*, Intrinsic noise, dissipation cost, and robustness of cellular networks: The underlying energy landscape of MAPK signal transduction. Proc. Natl. Acad. Sci. USA 105, 6039-6044 - - 2008 -
26)  Q. Lu, J. Wang*, "Single Molecule Conformational Dynamics of Adenylate Kinase: Energy Landscape, Structural Correlations, and Transition State Ensembles". J. Amer. Chem. Soc. 130, 4772 - - 2008 -
27) J. Wang*, X. Zheng, Y. Yang, D. Drueckhammer, W. Yang, G. Verkhivker, E. K. Wang, Quantifying intrinsic specificity: A potential complement to affinity in drug screening. Phys. Rev. Lett. 99, 198101 - - 2007 -
28) Q. Lu, P. H. Lu, J. Wang*, Exploring the mechanism of flexible biomolecular recognition with single molecule dynamics. Phys. Rev. Lett. 98, 128105 - - 2007 -
29) J. Chahine, R. J. Oliveira, V. B. P. Leite, and J. Wang*, Configuration-dependent diffusion can shift the kinetic transition state and barrier height of protein folding. Proc. Natl. Acad. Sci. USA 104, 14646-14651 - - 2007 -
30) B. A. Shoemaker, J. Wang, P. G. Wolynes, Structure Correlations in Protein Folding Funnels. Proc. Natl. Acad. Sci. USA 94, 777-782 - - 1997 -
 
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