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汤朝晖
单位:中国科学院长春应用化学研究所生态环境高分子材料重点实验室
地址:吉林省长春市人民大街5625号
邮编:130022
电话:0431-85262449
个人主页:
实验室介绍:
 
个人简历 Personal resume
汤朝晖 博士 研究员
工作单位:中国科学院长春应用化学研究所,生态环境高分子材料重点实验室
学习经历
1999 – 2005 中国科学院长春应用化学研究所,高分子化学与物理专业,理学博士,导师:陈学思 研究员;
1995 – 1999湘潭大学化学系,理学学士;
工作经历
2015 –  研究员,中国科学院长春应用化学研究所;
2009 – 2014 副研究员,中国科学院长春应用化学研究所;
2007 – 2008 博士后,美国纽约州立大学石溪分校(State University of New York at Stony Brook),合作导师:朱鹏年(Benjamin Chu),萧守道(Benjamin S. Hsiao);
2005 – 2006 研究助理,英国帝国理工学院(Imperial College London),合作导师:VC Gibson。
研究兴趣
生物医用高分子材料,药物缓控释
学术论文与专利情况
发表SCI研究论文80余篇,包括Progress in Polymer Science, Chemical Science, Biomateials, Journal of Controlled Release等,他引2000余次,授权专利30项。
个人荣誉
1.	2015年入选中国科学院青年创新促进会优秀会员;
2.	2011年入选中国科学院青年创新促进会会员;
3.	汤朝晖,可降解医用高分子材料的基础及应用研究,吉林省科技进步奖,一等奖,排名第7,2011。
4.	汤朝晖,聚乳酸新材料关键技术研发与产业化应用,中国石油与化学工业联合会技术发明奖,一等奖,排名第6,2011。

主持或参加科研项目(课题)
1.	国家自然科学基金面上项目,2016年,高分子纳米化CD47抗体用于恶性肿瘤的研究,62万元,主持;
2.	中国科学院青年创新促进会优秀会员,2015年,优秀会员人才专项经费,150万元,主持;
3.	国家自然科学基金面上项目,51373168,物理化学性质和肿瘤种类对高分子纳米粒子在小鼠体内代谢和分布的影响研究,2014/01 – 2017/12,80万元,主持;
4.	国家科技重大专项重大新药创制,2014ZX09507-009,IPT-ZHW155的临床前研究,2014/01 – 2016/12,40.5万元,参加(子课题副组长);
5.	吉林省医药产业发展专项资金项目,20130727050YY,聚谷氨酸接枝聚乙二醇药用辅料及顺铂胶束制剂的研究和开发,2013/06 – 2016/05,50万元,主持;
6.	国家科技重大专项重大新药创制,2013ZX09J13110-11B,基于生物可降解高分子电纺丝技术的战伤救治药物体系,2013/01 – 2015/12,110万元参加(子课题副组长);
7.	吉林省科技发展计划项目,科技支撑计划,重点科技攻关项目,20130206066GX,用于抗肿瘤药物靶向控释的高分子载体材料的研究和开发,2013/01 – 2015/12,18万元,主持;
8.	国家自然科学基金面上项目,51173184,氧化还原和pH双敏感的纳米药物控释系统及其克服肿瘤多药耐药性研究,2012/01 – 2015/12,65万元,主持;
9.	中国科学院青年创新促进会会员,2011年,会员人才专项经费,40万元,主持;
10.	国家自然科学青年基金,2009年,具有生物分子识别功能可生物降解高分子材料的合成与应用,23万元,主持。
学术论文与书籍章节目录
[1] Y. Zhang, C. Xiao, J. Ding, M. Li, X. Chen, Z. Tang, X. Zhuang, X. Chen, A comparative study of linear, Y-shaped and linear-dendritic methoxy poly(ethylene glycol)-block-polyamidoamine-block-poly(l-glutamic acid) block copolymers for doxorubicin delivery in vitro and in vivo, Acta Biomater. 40 (2016) 243-253.
[2] H. Yu, Z. Tang, M. Li, W. Song, D. Zhang, Y. Zhang, Y. Yang, H. Sun, M. Deng, X. Chen, Cisplatin loaded poly(L-glutamic acid)-g-methoxy poly(ethylene glycol) complex nanoparticles for potential cancer therapy: preparation, in vitro and in vivo evaluation, J Biomed Nanotechnol. 12(1) (2016) 69-78.
[3] Y. Wang, S. Lv, M. Deng, Z. Tang, X. Chen, A charge-conversional intracellular-activated polymeric prodrug for tumor therapy, Polym. Chem. 7 (2016) 2253-2263.
[4] Z. Tang, C. He, H. Tian, J. Ding, B.S. Hsiao, B. Chu, X. Chen, Polymeric nanostructured materials for biomedical applications, Prog. Polym. Sci. 60 (2016) 86-128.
[5] W. Song, Z. Tang, D. Zhang, X. Wen, S. Lv, Z. Liu, M. Deng, X. Chen, Solid Tumor Therapy Using a Cannon and Pawn Combination Strategy, Theranostics 6(7) (2016) 1023-1030.
[6] W. Song, Z. Tang, D. Zhang, M. Li, J. Gu, X. Chen, A cooperative polymeric platform for tumor-targeted drug delivery, Chemical Science 7(1) (2016) 728-736.
[7] W. Song, Z. Tang, N. Shen, H. Yu, Y. Jia, D. Zhang, J. Jiang, C. He, H. Tian, X. Chen, Combining disulfiram and poly(l-glutamic acid)-cisplatin conjugates for combating cisplatin resistance, J. Control. Release 231 (2016) 94-102.
[8] W. Song, Z. Tang, T. Lei, X. Wen, G. Wang, D. Zhang, M. Deng, X. Tang, X. Chen, Stable loading and delivery of disulfiram with mPEG-PLGA/PCL mixed nanoparticles for tumor therapy, Nanomed. Nanotechnol. Biol. Med. 12(2) (2016) 377-86.
[9] Y. Niu, W. Song, D. Zhang, Z. Tang, M. Deng, X. Chen, Functional computer-to-plate near-infrared absorbers as highly efficient photoacoustic dyes, Acta Biomater. 43 (2016) 262-8.
[10] C. He, Z. Tang, H. Tian, X. Chen, Co-delivery of chemotherapeutics and proteins for synergistic therapy, Adv. Drug Del. Rev. 98 (2016) 64-76.
[11] J. Chen, L. Lin, Z. Guo, C. Xu, Y. Li, H. Tian, Z. Tang, C. He, X. Chen, N-Isopropylacrylamide Modified Polyethylenimines as Effective siRNA Carriers for Cancer Therapy, Journal of Nanoscience and Nanotechnology 16(6) (2016) 5464-5469.
[12] Z. Ahmad, S. Lv, Z. Tang, A. Shah, X. Chen, Methoxy poly (ethylene glycol)-block-poly (glutamic acid)-graft-6-(2-nitroimidazole) hexyl amine nanoparticles for potential hypoxia-responsive delivery of doxorubicin, J. Biomater. Sci. Polym. Ed. 27(1) (2016) 40-54.
[13] 马丽莉, 邵俊, 杨晨光, 汤朝晖, 陈学思, PDLA-PBS-PDLA三嵌段共聚物的合成及性能, 高等学校化学学报 36(11) (2015) 2329-2334.
[14] H. Yu, Z. Tang, D. Zhang, W. Song, Y. Zhang, Y. Yang, Z. Ahmad, X. Chen, Pharmacokinetics, biodistribution and in vivo efficacy of cisplatin loaded poly(L-glutamic acid)-g-methoxy poly(ethylene glycol) complex nanoparticles for tumor therapy, J. Control. Release 205 (2015) 89-97.
[15] H. Yu, Z. Tang, D. Zhang, W. Song, T. Duan, J. Gu, X. Chen, Poly (ornithine‐co‐arginine‐co‐glycine‐co‐aspartic Acid): Preparation via NCA Polymerization and its Potential as a Polymeric Tumor‐Penetrating Agent, Macromol. Biosci. 15(6) (2015) 829–838.
[16] H. Yu, Z. Tang, W. Song, D. Zhang, Y. Zhang, X. Chen, Co-administration of iRGD enhancing the anticancer efficacy of cisplatin-loaded polypeptide nanoparticles, J. Control. Release 213 (2015) e145-e146.
[17] H.Y. Yifei Li, Hai Sun, Jianguo Liu, Zhaohui Tang, Dan Wang, Lianyou Yu, Xuesi Chen, Cisplatin-loaded poly(L-glutamic acid)-g-methoxy poly(ethylene glycol) nanoparticles as a potential chemotherapeutic agent against osteosarcoma, Chin. J. Polym. Sci. 33(5) (2015) 763-771.
[18] W. Song, Z. Tang, D. Zhang, H. Yu, X. Chen, Coadministration of Vascular Disrupting Agents and Nanomedicines to Eradicate Tumors from Peripheral and Central Regions, Small 11(31) (2015) 3755-3761.
[19] W. Song, Z. Tang, D. Zhang, N. Burton, W. Driessen, X. Chen, Comprehensive studies of pharmacokinetics and biodistribution of indocyanine green and liposomal indocyanine green by multispectral optoacoustic tomography, RSC Adv. 5(5) (2015) 3807-3813.
[20] C. Shi, H. Yu, D. Sun, L. Ma, Z. Tang, Q. Xiao, X. Chen, Cisplatin-loaded polymeric nanoparticles: Characterization and potential exploitation for the treatment of non-small cell lung carcinoma, Acta Biomater. 18 (2015) 68–76.
[21] M.Q. Li, Z.H. Tang, Y. Zhang, S.X. Lv, Q.S. Li, X.S. Chen, Targeted delivery of cisplatin by LHRH-peptide conjugated dextran nanoparticles suppresses breast cancer growth and metastasis, Acta Biomater. 18 (2015) 132-143.
[22] M. Li, Z. Tang, D. Zhang, H. Sun, H. Liu, Y. Zhang, Y. Zhang, X. Chen, Doxorubicin-loaded polysaccharide nanoparticles suppress the growth of murine colorectal carcinoma and inhibit the metastasis of murine mammary carcinoma in rodent models, Biomaterials 51(0) (2015) 161-172.
[23] B. Feng, Z. Xu, F. Zhou, H. Yu, Q. Sun, D. Wang, Z. Tang, H. Yu, Q. Yin, Z. Zhang, Y. Li, Near infrared light-actuated gold nanorods with cisplatin-polypeptide wrapping for targeted therapy of triple negative breast cancer, Nanoscale 7(36) (2015) 14854-64.
[24] R. Zhao, X. Li, B. Sun, Y. Zhang, D. Zhang, Z. Tang, X. Chen, C. Wang, Electrospun chitosan/sericin composite nanofibers with antibacterial property as potential wound dressings, Int. J. Biol. Macromol. 68 (2014) 92-97.
[25] H. Yu, Z. Tang, W. Song, M. Deng, X. Chen, Current Status and Future Prospects of Polymeric Nanocarrier for Tumor Targeting, Chem. J. Chin. Univ.-Chin. 35(5) (2014) 903-916.
[26] W. Song, Z. Tang, D. Zhang, Y. Zhang, H. Yu, M. Li, S. Lv, H. Sun, M. Deng, X. Chen, Anti-tumor efficacy of c(RGDfK)-decorated polypeptide-based micelles co-loaded with docetaxel and cisplatin, Biomaterials 35(9) (2014) 3005-3014.
[27] W. Song, Z. Tang, M. Li, S. Lv, H. Sun, M. Deng, H. Liu, X. Chen, Polypeptide-based combination of paclitaxel and cisplatin for enhanced chemotherapy efficacy and reduced side-effects, Acta Biomater. 10(3) (2014) 1392-1402.
[28] J. Shao, Z. Tang, J. Sun, G. Li, X. Chen, Linear and Four-Armed Poly(L-lactide)-block-poly(D-lactide) Copolymers and Their Stereocomplexation with Poly(lactide)s, Journal of Polymer Science Part B-Polymer Physics 52(23) (2014) 1560-1567.
[29] Z. Qu, R. Duan, X. Pang, B. Gao, X. Li, Z. Tang, X. Wang, X. Chen, Living and Stereoselective Polymerization of Rac-Lactide by Bimetallic Aluminum Schiff-Base Complexes, Journal of Polymer Science Part a-Polymer Chemistry 52(9) (2014) 1344-1352.
[30] S. Lv, Z. Tang, D. Zhang, W. Song, M. Li, J. Lin, H. Liu, X. Chen, Well-defined polymer-drug conjugate engineered with redox and pH-sensitive release mechanism for efficient delivery of paclitaxel, J. Control. Release 194 (2014) 220-227.
[31] S. Lv, Z. Tang, M. Li, J. Lin, W. Song, H. Liu, Y. Huang, Y. Zhang, X. Chen, Co-delivery of doxorubicin and paclitaxel by PEG-polypeptide nanovehicle for the treatment of non-small cell lung cancer, Biomaterials 35(23) (2014) 6118-6129.
[32] S. Lv, W. Song, Z. Tang, M. Li, H. Yu, H. Hong, X. Chen, Charge-Conversional PEG-Polypeptide Polyionic Complex Nanoparticles from Simple Blending of a Pair of Oppositely Charged Block Copolymers as an Intelligent Vehicle for Efficient Antitumor Drug Delivery, Mol. Pharm. 11(5) (2014) 1562-1574.
[33] Q. Li, S. Lv, Z. Tang, M. Liu, D. Zhang, Y. Yang, X. Chen, A co-delivery system based on paclitaxel grafted mPEG-b-PLG loaded with doxorubicin: Preparation, in vitro and in vivo evaluation, Int. J. Pharm. 471(1–2) (2014) 412-420.
[34] M.-q. Li, Z.-h. Tang, C. Wang, Y. Zhang, H.-t. Cui, X.-s. Chen, Efficient side-chain modification of dextran via base-catalyzed epoxide ring-opening and thiol-ene click chemistry in aqueous media, Chin. J. Polym. Sci. 32(8) (2014) 969-974.
[35] M. Li, Z. Tang, Y. Zhang, S. Lv, H. Yu, D. Zhang, H. Hong, X. Chen, LHRH-peptide conjugated dextran nanoparticles for targeted delivery of cisplatin to breast cancer, J. Mat. Chem. B 2(22) (2014) 3490-3499.
[36] M. Li, Z. Tang, S. Lv, W. Song, H. Hong, X. Jing, Y. Zhang, X. Chen, Cisplatin crosslinked pH-sensitive nanoparticles for efficient delivery. of doxorubicin, Biomaterials 35(12) (2014) 3851-3864.
[37] M. Li, Z. Tang, J. Lin, Y. Zhang, S. Lv, W. Song, Y. Huang, X. Chen, Synergistic Antitumor Effects of Doxorubicin-Loaded Carboxymethyl Cellulose Nanoparticle in Combination with Endostar for Effective Treatment of Non-Small-Cell Lung Cancer, Adv. Healthc. Mater. 3(11) (2014) 1877-1888.
[38] Z. Guo, H. Tian, L. Lin, J. Chen, C. He, Z. Tang, X. Chen, Hydrophobic Polyalanine Modified Hyperbranched Polyethylenimine as High Efficient pDNA and siRNA Carrier, Macromol. Biosci. 14(10) (2014) 1406-1414.
[39] J. Chen, J. Xia, H. Tian, Z. Tang, C. He, X. Chen, Thermo-/pH-dual responsive properties of hyperbranched polyethylenimine grafted by phenylalanine, Arch. Pharm. Res. 37(1) (2014) 142-148.
[40] Z. Ahmad, Z. Tang, A. Shah, S. Lv, D. Zhang, Y. Zhang, X. Chen, Cisplatin Loaded Methoxy Poly (ethylene glycol)-block-Poly (L-glutamic acid-co-L-Phenylalanine) Nanoparticles against Human Breast Cancer Cell, Macromol. Biosci. 14(9) (2014) 1337-1345.
[41] L. Zhao, C. Xiao, J. Ding, P. He, Z. Tang, X. Pang, X. Zhuang, X. Chen, Facile one-pot synthesis of glucose-sensitive nanogel via thiol-ene click chemistry for self-regulated drug delivery, Acta Biomater. 9(5) (2013) 6535-6543.
[42] L. Zhao, J. Ding, C. Xiao, P. He, Z. Tang, X. Chen, Phenylboronic acid functionalized polypeptide micelles for glucose-responsive insulin release at physiological pH, J. Control. Release 172(1) (2013) E110-E110.
[43] S. Lv, M. Li, Z. Tang, W. Song, H. Sun, H. Liu, X. Chen, Doxorubicin-loaded amphiphilic polypeptide-based nanoparticles as an efficient drug delivery system for cancer therapy, Acta Biomater. 9(12) (2013) 9330-9342.
[44] M. Li, Z. Tang, H. Sun, J. Ding, W. Song, X. Chen, pH and reduction dual-responsive nanogel cross-linked by quaternization reaction for enhanced cellular internalization and intracellular drug delivery, Polym. Chem. 4(4) (2013) 1199-1207.
[45] M. Li, W. Song, Z. Tang, S. Lv, L. Lin, H. Sun, Q. Li, Y. Yang, H. Hong, X. Chen, Nanoscaled Poly(L-glutamic acid)/Doxorubicin-Amphiphile Complex as pH-responsive Drug Delivery System for Effective Treatment of Nonsmall Cell Lung Cancer, Acs Applied Materials & Interfaces 5(5) (2013) 1781-1792.
[46] M. Li, S. Lv, Z. Tang, W. Song, H. Yu, H. Sun, H. Liu, X. Chen, Polypeptide/Doxorubicin Hydrochloride Polymersomes Prepared Through Organic Solvent-free Technique as a Smart Drug Delivery Platform, Macromol. Biosci. 13(9) (2013) 1150-1162.
[47] D. Li, H. Sun, J. Ding, Z. Tang, Y. Zhang, W. Xu, X. Zhuang, X. Chen, Polymeric topology and composition constrained polyether-polyester micelles for directional antitumor drug delivery, Acta Biomater. 9(11) (2013) 8875-8884.
[48] Y. Huang, Z. Tang, X. Zhang, H. Yu, H. Sun, X. Pang, X. Chen, pH-Triggered Charge-Reversal Polypeptide Nanoparticles for Cisplatin Delivery: Preparation and In Vitro Evaluation, Biomacromolecules 14(6) (2013) 2023-2032.
[49] P. He, C.-w. Zhao, C.-s. Xiao, Z.-h. Tang, X.-s. Chen, Thermosensitive polyion complex micelles prepared by self-assembly of two oppositely charged diblock copolymers, Chin. J. Polym. Sci. 31(2) (2013) 318-324.
[50] P. He, H. Liu, Z. Tang, M. Deng, Y. Yang, X. Pang, X. Chen, Poly(ester amide) blend microspheres for oral insulin delivery, Int. J. Pharm. 455(1-2) (2013) 259-266.
[51] C. He, Z. Tang, H. Tian, X. Chen, Progress in the Development of Biomedical Polymer Materials Fabricated by 3-Dimensional Printing Technology, Acta Polymerica Sinica (6) (2013) 722-732.
[52] J. Guo, X. Li, H. Yu, Z. Tang, X. Tang, C. Cai, J. Xu, H. Xu, The anti-melanoma efficiency of the intratumoral injection of cucurbitacin-loaded sustained-release carriers: A PLGA particle system, J. Pharm. Sci. 102(8) (2013) 2550-2563.
[53] B. Gao, R. Duan, X. Pang, X. Li, Z. Qu, Z. Tang, X. Zhuang, X. Chen, Stereoselective Ring-Opening Polymerization of rac-Lactides Catalyzed by Aluminum Hemi-Salen Complexes, Organometallics 32(19) (2013) 5435-5444.
[54] L. Zhao, J. Ding, C. Xiao, P. He, Z. Tang, X. Pang, X. Zhuang, X. Chen, Glucose-sensitive polypeptide micelles for self-regulated insulin release at physiological pH, J. Mater. Chem. 22(24) (2012) 12319-12328.
[55] H. Tian, Z. Tang, X. Zhuang, X. Chen, X. Jing, Biodegradable synthetic polymers: Preparation, functionalization and biomedical application, Prog. Polym. Sci. 37(2) (2012) 237-280.
[56] W. Song, C. Xiao, L. Cui, Z. Tang, X. Zhuang, X. Chen, Facile construction of functional biosurface via SI-ATRP and "click glycosylation", Colloid Surf. B-Biointerfaces 93 (2012) 188-194.
[57] W. Song, Z. Tang, M. Li, S. Lv, H. Yu, L. Ma, X. Zhuang, Y. Huang, X. Chen, Tunable pH-Sensitive Poly(beta-amino ester)s Synthesized from Primary Amines and Diacrylates for Intracellular Drug Delivery, Macromol. Biosci. 12(10) (2012) 1375-1383.
[58] W. Song, M. Li, Z. Tang, Q. Li, Y. Yang, H. Liu, T. Duan, H. Hong, X. Chen, Methoxypoly(ethylene glycol)-block-Poly(L-glutamic acid)-Loaded Cisplatin and a Combination With iRGD for the Treatment of Non-Small-Cell Lung Cancers, Macromol. Biosci. 12(11) (2012) 1514-1523.
[59] D. Li, J.X. Ding, Z.H. Tang, H. Sun, X.L. Zhuang, J.Z. Xu, X.S. Chen, In vitro evaluation of anticancer nanomedicines based on doxorubicin and amphiphilic Y-shaped copolymers, Int. J. Nanomedicine 7 (2012) 2687-2697.
[60] P. He, Z. Tang, L. Lin, M. Deng, X. Pang, X. Zhuang, X. Chen, Novel Biodegradable and pH-Sensitive Poly(ester amide) Microspheres for Oral Insulin Delivery, Macromol. Biosci. 12(4) (2012) 547-556.
[61] C. He, X. Zhuang, Z. Tang, H. Tian, X. Chen, Stimuli-Sensitive Synthetic Polypeptide-Based Materials for Drug and Gene Delivery, Adv. Healthc. Mater. 1(1) (2012) 48-78.
[62] 汤朝晖, 陈学思, 新型药控/缓释材料, 中国新材料产业发展报告(2010)2011.
[63] X.-l. Zhuang, H.-y. Yu, Z.-h. Tang, K. Oyaizu, H. Nishide, X.-s. Chen, Polymerization of lactic O-carboxylic anhydride using organometallic catalysts, Chin. J. Polym. Sci. 29(2) (2011) 197-202.
[64] L. Zhao, J. Ding, P. He, C. Xiao, Z. Tang, X. Zhuang, X. Chen, An efficient pH sensitive oral insulin delivery system enhanced by deoxycholic acid, J. Control. Release 152 (2011) E184-E186.
[65] W. Wang, J. Ding, C. Xiao, Z. Tang, D. Li, J. Chen, X. Zhuang, X. Chen, Synthesis of Amphiphilic Alternating Polyesters with Oligo(ethylene glycol) Side Chains and Potential Use for Sustained Release Drug Delivery, Biomacromolecules 12(7) (2011) 2466-2474.
[66] J. Ding, X. Zhuang, C. Xiao, Y. Cheng, L. Zhao, C. He, Z. Tang, X. Chen, Preparation of photo-cross-linked pH-responsive polypeptide nanogels as potential carriers for controlled drug delivery, J. Mater. Chem. 21(30) (2011) 11383-11391.
[67] J. Ding, C. Xiao, L. Zhao, Y. Cheng, L. Ma, Z. Tang, X. Zhuang, X. Chen, Poly(L-glutamic acid) Grafted with Oligo(2-(2-(2-methoxyethoxy)ethoxy) ethyl methacrylate): Thermal Phase Transition, Secondary Structure, and Self-Assembly, Journal of Polymer Science Part a-Polymer Chemistry 49(12) (2011) 2665-2676.
[68] J. Ding, C. Xiao, L. Yan, Z. Tang, X. Zhuang, X. Chen, X. Jing, pH and dual redox responsive nanogel based on poly(l-glutamic acid) as potential intracellular drug carrier, J. Control. Release 152 (2011) E11-E13.
[69] J. Ding, C. Xiao, Z. Tang, X. Zhuang, X. Chen, Highly Efficient "Grafting From" an alpha-Helical Polypeptide Backbone by Atom Transfer Radical Polymerization, Macromol. Biosci. 11(2) (2011) 192-198.
[70] C. Xiao, C. Zhao, P. He, Z. Tang, X. Chen, X. Jing, Facile Synthesis of Glycopolypeptides by Combination of Ring-Opening Polymerization of an Alkyne-Substituted N-carboxyanhydride and Click "Glycosylation", Macromol. Rapid Commun. 31(11) (2010) 991-997.
[71] F. Wan, Z. Tang, W. He, B. Chu, A chemistry/physics pathway with nanofibrous scaffolds for gene delivery, PCCP 12(39) (2010) 12379-12389.
[72] X. Pang, X. Zhuang, Z. Tang, X. Chen, Polylactic acid (PLA): Research, development and industrialization, Biotechnology Journal 5(11) (2010) 1125-1136.
[73] Z.H. Tang, C.Q. Qiu, J.R. McCutcheon, K. Yoon, H.Y. Ma, D.F. Fang, E. Lee, C. Kopp, B.S. Hsiao, B. Chu, Design and Fabrication of Electrospun Polyethersulfone Nanofibrous Scaffold for High-Flux Nanofiltration Membranes, Journal of Polymer Science Part B-Polymer Physics 47(22) (2009) 2288-2300.
[74] Z. Tang, J. Wei, L. Yung, B. Ji, H. Ma, C. Qiu, K. Yoon, F. Wan, D. Fang, B.S. Hsiao, B. Chu, UV-cured poly(vinyl alcohol) ultrafiltration nanofibrous membrane based on electrospun nanofiber scaffolds, J. Membr. Sci. 328(1-2) (2009) 1-5.
[75] Z. Tang, V.C. Gibson, rac-Lactide polymerization using aluminum complexes bearing tetradentate phenoxy-amine ligands, Eur. Polym. J. 43(1) (2007) 150-155.
[76] Y.K. Yang, Z.H. Tang, X. Pang, H.Z. Du, X.S. Chen, X.B. Jing, Stereoselective polymerization of rac-lactide initiated by achiral Schiff-base isopropoxide aluminum complex, Chem. J. Chin. Univ.-Chin. 27(2) (2006) 352-355.
[77] Z. Tang, X. Pang, J. Sun, H. Du, X. Chen, Five-coordinated active species in the stereoselective polymerization of rac-lactide using N,N '-(2,2-dimethyl-1,3-propylene)bis(3,5-di-tert-butyl-salicylideneimine) aluminum complexes, Journal of Polymer Science Part a-Polymer Chemistry 44(16) (2006) 4932-4938.
[78] Z.H. Tang, Y.K. Yang, X. Pang, J.L. Hu, X.S. Chen, N.H. Hu, X.B. Jing, Controlled and stereospecific polymerization of rac-lactide with a single-site ethyl aluminum and alcohol initiating system, J. Appl. Polym. Sci. 98(1) (2005) 102-108.
[79] J.L. Hu, Z.H. Tang, X.Y. Qiu, X. Pang, Y.K. Yang, X.S. Chen, X.B. Jing, Formation of flower-or cake-shaped stereocomplex particles from the stereo multiblock copoly(rac-lactide)s, Biomacromolecules 6(5) (2005) 2843-2850.
[80] J. Hu, Z. Tang, X. Qiu, Y. Han, Q. Du, X. Chen, X. Jing, Effects of Stereoregularity of Multiblock Copoly(rac-lactide)s on Stereocomplex Microparticles and Their Insulin Delivery, Macromol. Biosci. 5(12) (2005) 1193-1199.
[81] H.L. Guan, Z.G. Xie, Z.H. Tang, X.Y. Xu, X.S. Chen, X.B. Jing, Preparation of block copolymer of epsilon-caprolactone and 2-methyl-2-carboxyl-propylene carbonate, Polymer 46(8) (2005) 2817-2824.
[82] C. Deng, G.Z. Rong, H.Y. Tian, Z.H. Tang, X.S. Chen, X.B. Jing, Synthesis and characterization of poly(ethylene glycol)-b-poly (L-lactide)-b-poly(L-glutamic acid) triblock copolymer, Polymer 46(3) (2005) 653-659.
[83] Z.H. Tang, X.S. Chen, Y.K. Yang, X. Pang, J.R. Sun, X.F. Zhang, X.B. Jing, Stereoselective polymerization of rac-lactide with a bulky aluminum/Schiff base complex, Journal of Polymer Science Part a-Polymer Chemistry 42(23) (2004) 5974-5982.
[84] Z.H. Tang, X.S. Chen, X. Pang, Y.K. Yang, X.F. Zhang, X.B. Jing, Stereoselective polymerization of rac-lactide using a monoethylaluminum Schiff base complex, Biomacromolecules 5(3) (2004) 965-970.
[85] J.R. Sun, Z.K. Hong, L.X. Yang, Z.H. Tang, X.S. Chen, X.B. Jing, Study on crystalline morphology of poly(L-lactide)-poly(ethylene glycol) diblock copolymer, Polymer 45(17) (2004) 5969-5977.
[86] Z.H. Tang, X.S. Chen, Q.Z. Hang, X.C. Bian, L.X. Yang, L.H. Piao, X.B. Jing, Strontium-based initiator system for ring-opening polymerization of cyclic esters, Journal of Polymer Science Part a-Polymer Chemistry 41(13) (2003) 1934-1941.
[87] G.Z. Rong, M.X. Deng, C. Deng, Z.H. Tang, L.H. Piao, X.S. Chen, X.B. Jing, Synthesis of poly(epsilon-caprolactone)-b-poly(gamma-benzyl-L-glutamic acid) block copolymer using amino organic calcium catalyst, Biomacromolecules 4(6) (2003) 1800-1804.
专利目录(部分)
1.	汤朝晖;孙环娇;于海洋;吕世贤;张大为;陈学思 一种高分子抗肿瘤前药及其制备方法. CN201410417521.7, 2014.
2.	汤朝晖; 李明强; 于海洋; 宋万通; 陈学思 改性聚多糖及其制备方法. CN201410133893.7, 2014.
3.	汤朝晖; 李明强; 林坚; 宋万通; 陈学思 聚多巴胺纳米粒子的应用. CN201410177537.5, 2014.
4.	汤朝晖; 李明强; 高中辉; 于海洋; 陈学思 一种聚苯胺纳米粒子的制备方法及其应用. CN201410177564.2, 2014.
5.	汤朝晖;于海洋;宋万通;李明强;陈学思 阿霉素复合物及其制备方法. CN201310002466.0, 2013.
6.	汤朝晖;宋万通;于海洋;李明强;陈学思 二氯-1,2-环己二胺合铂配合物及其制备方法. CN201310361430.1, 2013.
7.	汤朝晖;吕世贤;陈学思;李明强;宋万通;于海洋 氨基酸嵌段共聚物及其制备方法和复合物. CN201310009638.7, 2013.
8.	汤朝晖;李明强;宋万通;陈学思 一种二价双核铂配合物及其制备方法. CN201310361461.7, 2013.
9.	汤朝晖;李明强;陈学思;张影 乙二胺四乙酸双核铂配合物及其制备方法. CN201310449569.1, 2013.
10.	汤朝晖; 李雪; 于海洋; 张大为; 宋万通; 陈学思 一种创伤止血敷料的制备方法. CN201310547279.0, 2013.
11.	汤朝晖; 李明强; 林坚; 宋万通; 吕世贤; 陈学思 共担载顺铂和阿霉素的复合物、胶束及胶束的制备方法. CN201310039396.6, 2013.
12.	孙海; 汤朝晖; 许午; 高战团; 庄秀丽; 陈学思 一种紫杉醇高分子键合药及其制备方法. CN201310588848.6, 2013.
13.	汤朝晖; 于海洋; 宋万通; 李明强; 庄秀丽; 陈学思 顺铂配合物及其制备方法. CN201210382696.X, 2012.
14.	汤朝晖; 宋万通; 吕世贤; 于海洋; 陈学思 一种聚乙二醇-聚β-胺酯嵌段共聚物及其制备方法. CN201210311209.0, 2012.
15.	汤朝晖; 宋万通; 李明强; 丁建勋; 于海洋; 陈学思 一种聚氨基酸接枝共聚物及其制备方法. CN201210391089.X, 2012.
16.	汤朝晖; 李明强; 宋万通; 吕世贤; 陈学思; 庄秀丽 阿霉素纳米粒及其制备方法. CN201210034414.7, 2012.
17.	汤朝晖; 李明强; 宋万通; 丁建勋; 陈学思; 庄秀丽 阿霉素复合物、胶束及胶束的制备方法. CN201210034443.3, 2012.
18.	汤朝晖; 李明强; 宋万通; 陈学思; 陈杰; 庄秀丽 顺铂配合物及其制备方法. CN201210034430.6, 2012.
19.	汤朝晖; 黄月; 陈学思 一种顺铂配合物及其制备方法. CN201210430624.8, 2012.
20.	陈学思; 赵丽; 肖春生; 丁建勋; 何盼; 汤朝晖 聚合物、葡萄糖纳米凝胶、葡萄糖纳米凝胶组合物及其制备方法. CN201210512665.1, 2012.
21.	庄秀丽; 丁建勋; 肖春生; 贺超良; 汤朝晖; 陈学思 聚氨基酸接枝共聚物及其制备方法. CN201110023705.1, 2011.
22.	庄秀丽; 丁建勋; 栗迪; 汤朝晖; 陈学思 聚氨基酸嵌段共聚物及其制备方法. CN201110343619.9, 2011.
23.	汤朝晖; 赵丽; 丁建勋; 肖春生; 何盼; 陈学思 共聚物、葡萄糖敏感胶束、葡萄糖敏感载药胶束及其制备方法. CN201110260560.7, 2011.
24.	汤朝晖; 赵丽; 丁建勋; 何盼; 肖春生; 庄秀丽; 陈学思 一种胰岛素载药微球及其制备方法. CN201110023708.5, 2011.
25.	汤朝晖; 栗迪; 丁建勋; 孙海; 庄秀丽; 陈学思 嵌段共聚物及其制备方法. CN201110325770.X, 2011.
26.	汤朝晖; 栗迪; 丁建勋; 孙海; 庄秀丽; 陈学思 抗肿瘤前药及其制备方法. CN201110149748.4, 2011.
27.	陈学思; 何盼; 汤朝晖; 庄秀丽; 林琳 胰岛素载药微球及其制备方法. CN201110368851.8, 2011.
28.	庄秀丽; 高晓晔; 汤朝晖; 陈学思 一种聚(L-谷氨酸)/聚丙烯酸水凝胶及其制备方法. CN201010130914.1, 2010.
29.	庄秀丽; 丁建勋; 赵丽; 肖春生; 汤朝晖; 陈学思 一种聚合物微凝胶及其制备方法. CN201010130890.X, 2010.
30.	庄秀丽; 丁建勋; 肖春生; 成一龙; 赵丽; 汤朝晖; 陈学思 聚(L-谷氨酸)均聚物、无规共聚物、接枝共聚物及其制备方法. CN201010563665.5, 2010.
31.	庄秀丽; 丁建勋; 汤朝晖; 陈学思 一种功能化聚酯及其制备方法. CN201010130905.2, 2010.
32.	庄秀丽; 丁建勋; 汤朝晖; 陈学思 聚合物纳米水凝胶及其制备方法. CN201010561226.0, 2010.
33.	庄秀丽; 丁建勋; 高晓晔; 肖春生; 汤朝晖; 陈学思 聚合物纳米水凝胶及其制备方法. CN201010563357.2, 2010.
34.	庄秀丽; 丁建勋; 肖春生; 赵长稳; 汤朝晖; 陈学思 氯乙醇功能化聚(L-谷氨酸)均聚与无规共聚物及制法和应用. CN200910218013.5, 2009.

 
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