访问量:15054
 
郭昌
单位:微尺度物质科学国家研究中心
地址:安徽合肥金寨路96号中国科学技术大学东区
邮编:230026
电话:
个人主页:
实验室介绍:
 
个人简历 Personal resume
教育与科研经历
2017.02-至今  特任研究员,中国科学技术大学,合肥微尺度物质科学国家实验室
2013.08-2017.01  博士后,德国明斯特大学
2007.09-2013.06  博士,中国科学技术大学
2003.08-2007.06  学士, 中国科学技术大学
主要研究方向
研究工作主要集中在不对称合成方向,以新型不对称催化研究为基础,发展惰性化学键的直接手性官能团化反应,建立手性催化模型,提高反应活性与选择性,并将这些方法学用于天然产物的合成,发展高效、原子经济性和环境友好的现代有机合成化学。
 
研究方向 Research direction
1、不对称催化
2、电化学合成
3、生物活性分子合成
 
招生信息 Enrollment information
电化学及有机合成方向,热爱科研,工作认真负责,遵守工作纪律,具有团队合作精神。
 
论文专著 The monograph
1) Ni/Chiral Sodium Carboxylate Dual Catalyzed Asymmetric O-Propargylation - J. Am. Chem. Soc. - 2021 - 143, 21048
2) Copper-Catalyzed Enantioselective Difluoromethylation of Amino Acids via Difluorocarbene. - J. Am. Chem. Soc. - 2021 - 143, 6376
3) Collective synthesis of acetylenic pharmaceuticals via enantioselective Nickel/Lewis acid-catalyzed propargylic alkylation. - Nat. Commum. - 2021 - 12, 299.
4) Asymmetric Electrochemical Arylation in the Formal Synthesis of (+)-Amurensinine. - CCS Chem. - 2021 - 3, 338
5) Cooperative Ni/Cu-Catalyzed Asymmetric Propargylic Alkylation of Aldimine Esters. - Angew. Chem. Int. Ed. - 2020 - 59, 14270
6) Merging Electrosynthesis and Bifunctional Squaramide Catalysis in the Asymmetric Detrifluoroacetylative Alkylation Reactions. - Angew. Chem. Int. Ed. - 2020 - 59, 18500
7) Asymmetric Electrochemical Transformation - Angew. Chem. Int. Ed. - 2020 - 59, 12612
8) Asymmetric Lewis Acid Catalyzed Electrochemical Alkylation - Angew. Chem. Int. Ed. - 2019 - 58, 6999
9) Enantioselective γ‐Addition of Pyrazole and Imidazole Heterocycles to Allenoates Catalyzed by Chiral Phosphine - Angew. Chem. Int. Ed. - 2019 - 58, 2854
10) Electrochemical Reductive Smiles Rearrangement for C−N Bond Formation - Org. Lett. - 2019 - 21, 10
11) Switchable Smiles Rearrangement for Enantioselective O-Aryl Amination - Org. Lett. - 2019 - 21, 4915
12) Enantioselective [4+2] Annulation to the Concise Synthesis of Chiral Dihydrocarbazoles - iScience - 2020 - 23, 100840
13) Cooperative N-Heterocyclic Carbene/Palladium-Catalyzed Enantioselective Umpolung Annulations - Journal of the American Chemical Society - 2016 - 138,7840.
14) Mechanistic studies on a cooperative NHC organocatalysis/palladium catalysis system: uncovering significant lessons for mixed chiral Pd(NHC)(PR3) catalyst design - J. Am. Chem. Soc. - 2017 - 139, 4443
15) Switchable selectivity in an NHC-catalysed dearomatizing annulation reaction - Nature Chemistry - 2015 - 7, 843.
16) N-Heterocyclic Carbene Catalyzed Switchable Reactions of Enals with Azoalkenes: Formal [4+3] and [4+1] Annulations for the Synthesis of 1,2-Diazepines and Pyrazoles - Journal of the American Chemical Society - 2014 - 136, 17402.
17) N-Heterocyclic Carbene Catalyzed Formal [3+2] Annulation Reaction of Enals: An Efficient Enantioselective Access to Spiro-Heterocycles - Angewandte Chemie-International Edition - 2014 - 53, 10232.
18) Core-Structure-Oriented Asymmetric Organocatalytic Substitution of 3-Hydroxyoxindoles: Application in the Enantioselective Total Synthesis of (+)-Folicanthine - Angewandte Chemie-International Edition - 2012 - 51, 1046.
19) Enantioselective Oxidative Cross-Coupling Reaction of 3-Indolylmethyl C-H Bonds with 1,3-Dicarbonyls Using a Chiral Lewis Acid-Bonded Nucleophile to Control Stereochemistry - Angewandte Chemie-International Edition - 2010 - 49,5558.
20)  Organocatalytic asymmetric formal [3+2]cycloaddition reaction of isocyanoesters to nitroolefins leading to highly optically active dihydropyrroles - Angewandte Chemie-International Edition - 2008 - 47, 3414.
21) Biomimetic Asymmetric 1,3-Dioplar Cycloaddition: Amino Acid Precursors in Biosynthesis Serve as Latent Azomethine Ylides - Organic Letters - 2013 - 15, 2676.
 
报考意向 Ambition
 
 
 

如果有意向报考此老师的硕士或博士,请留下你的信息。

 
  姓  名: 移动电话:
  电子邮箱: 所学专业:
  毕业院校: 报考类型: 博士 硕士
  国  别:
  个人照片: ( 支持格式:JPEG,JPG,PNG,GIF文件大小请勿超过1M)
 

个人简历:

( 支持格式:PDF,DOC,DOCX,JPG,JPEG,文件大小请勿超过1M)
  成 绩 单: ( 支持格式:PDF,DOC,DOCX,JPG,JPEG,文件大小请勿超过1M)
  备注:
(限150字)
 
   
         
         
         
 
COPYRIGHT 2007 中国科学技术大学研究生院、校学位办 All Rights Reserved 地址:安徽省合肥市金寨路96号 邮编:230026。
TEL:+86-551-63602928 FAX:+86-551-63602179 E-mail:gradschl@ustc.edu.cn