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缪鹏
单位:中国科学院苏州生物医学工程技术研究所
地址:江苏省苏州市高新区科灵路88号
邮编:215163
电话:0512-69588279
个人主页: http://sourcedb.sibet.cas.cn/zw/yjdw/yjy/201602/t20160222_4534896.html
实验室介绍:
 
个人简历 Personal resume
    缪鹏,博士,研究员,英国皇家化学会会士。1986年出生于江苏南通。2011年入职中科院苏州生物医学工程技术研究所,任研究实习员,2013年晋升为助理研究员,2015年破格晋升为副研究员,2018年破格晋升为研究员,2019年任博士生导师。
    从事生物医学传感、DNA纳米技术等方面的研究工作,作为负责人承担国家自然科学基金面上项目/青年基金、国家重点研发计划子课题、国家重大科研装备研制项目子课题、博士后创新人才支持计划、江苏省自然科学基金、江苏省产学研合作项目、苏州市科技计划等多个项目/课题。入选全球Top 1%高被引作者(Royal Society of Chemistry),江苏省“六大人才高峰”高层次人才,江苏省“333高层次人才培养工程”等。
    已发表SCI收录论文120余篇,包括7篇Anal. Chem. (IF=6.35),2篇J. Mater. Chem. A (IF=10.733),7篇Biosens. Bioelectron. (IF=9.518),5篇ACS Appl. Mater. Interfaces (IF=8.456);出版英文专著1部;授权发明专利18件;H-index为26;多篇论文入选ESI高被引论文及期刊封面。担任Scientific Reports期刊编委,担任Adv. Mater., Adv. Funct. Mater., Chem. Sci., ACS Nano, Anal. Chem., Biosens. Bioelectron., Theranostics, Nanoscale等多个期刊的审稿人。
 
研究方向 Research direction
1、生物分析化学
2、DNA纳米技术
 
招生信息 Enrollment information
招收化学、生物学、生物医学工程等专业背景的硕士/博士研究生。
 
论文专著 The monograph Researcher ID
1) Fabrication of polymeric ferrocene nanoparticles for electrochemical aptasensing of protein with target catalyzed hairpin assembly - Anal. Chem. - 2019 - 2019, 91
2) Bipedal DNA walker based electrochemical genosensing strategy - Anal. Chem. - 2019 - 2019, 91
3) Polydopamine nanosphere@silver nanoclusters for fluorescent detection of multiplex tumor markers - Nanoscale - 2019 - 2019, 11
4) Silver nanoparticle@DNA tetrahedron based colorimetric detection of HIV-related DNA with cascade strand displacement amplification - J. Mater. Chem. B - 2019 - 2019, 7
5) FRET investigation toward DNA tetrahedron-based ratiometric analysis of intracellular telomerase activity - J. Mater. Chem. B - 2019 - 2019, 7
6) Carbon nanodots based fluorescent method for virus DNA analysis with isothermal strand displacement amplification - Part. Part. Syst. Charact. - 2019 - 2019, 36
7) Electrochemical detection of T4 polynucleotide kinase based on target-assisted ligation reaction coupled with silver nanoparticles - Anal. Chim. Acta - 2019 - 2019, 1085
8) Peptide cleavage-based electrochemical biosensor coupling graphene oxide and silver nanoparticles - Anal. Chim. Acta - 2019 - 2019, 1047
9) A ratiometric electrochemical assay for human 8-oxoguanine DNA glycosylase amplified by hybridization chain reaction - Electrochem. Commun. - 2019 - 2019, 103
10) Electrochemical impedance spectroscopic analysis of nucleic acids through DNA tetrahedron self-walking machine - Electrochem. Commun. - 2019 - 2019, 101
11) Star trigon structure-aided DNA walker for amplified electrochemical detection of DNA - Electrochem. Commun. - 2019 - 2019, 99
12) Preparation of a novel iron cryptate as an electrochemical probe for biosensing - Electrochem. Commun. - 2019 - 2019, 98
13) Chameleon silver nanoclusters for ratiometric sensing of miRNA - Sens. Actuators, B - 2019 - 2019, 297
14) Ratiometric electrochemical sensing strategy for the ultrasensitive detection of telomerase activity - ChemElectroChem - 2019 - 2019, 6
15) Copper (II)-ploy-L-histidine functionalized multi walled carbon nanotubes as efficient mimetic enzyme for sensitive electrochemical detection of salvianic acid A - Biosens. Bioelectron. - 2018 - 2018, 121
16) Hand-in-hand RNA nanowire-based aptasensor for the detection of theophylline - Biosens. Bioelectron. - 2018 - 2018, 101
17) DNA-functionalized porous Fe3O4 nanoparticles for the construction of self-powered miRNA biosensor with target recycling amplification - ACS Appl. Mater. Interfaces - 2018 - 2018, 10
18) Electrochemical detection of miRNA combining T7 exonuclease-assisted cascade signal amplification and DNA-templated copper - Anal. Chem. - 2018 - 2018, 90
19) Triple signal amplification strategy for ultrasensitive determination of miRNA based on duplex specific nuclease and bridge DNA-gold nanoparticles - Anal. Chem. - 2018 - 2018, 90
20) Ultrasensitive detection of DNA based on exonuclease III-assisted recycling amplification and DNAzyme motor - Bioconjug. Chem. - 2018 - 2018, 29
21) Electrochemical determination of Ca2+ based on recycling formation of highly selective DNAzyme and gold nanoparticles-mediated amplification - Bioconjug. Chem. - 2018 - 2018, 29
22) A colorimetric aptasensor for the antibiotics oxytetracycline and kanamycin based on the use of magnetic beads and gold nanoparticles - Microchim. Acta - 2018 - 2018, 185
23) Ultrasensitive electrochemical detection of miRNA based on DNA strand displacement polymerization and Ca2+-dependent DNAzyme cleavage - Analyst - 2018 - 2018, 143
24) DNA-templated copper nanoparticles for voltammetric analysis of endonuclease activity - Analyst - 2018 - 2018, 143
25) Hydrothermal synthesis of N,S co-doped carbon nanodots for highly selective detection of living cancer cells - J. Mater. Chem. B - 2018 - 2018, 6
26) A PCR-free voltammetric method for telomerase activity assay using a substrate primer on a gold electrode and DNA-triggered capture of gold nanoparticles - Microchim. Acta - 2018 - 2018, 185
27) Electrochemical detection of arsenic contamination based on hybridization chain reaction and RecJf exonuclease-mediated amplification - Chem. Eng. J. - 2018 - 2018, 353
28) Electrochemical sensing of attomolar miRNA combining cascade strand displacement polymerization and reductant-mediated amplification - Chem. Commun. - 2018 - 2018, 54
29) A novel mode of DNA assembly at electrode and its application to protein quantification - Anal. Chim. Acta - 2018 - 2018, 1029
30) An ultrasensitive aptasensor for prostate specific antigen assay based on Exonuclease T-aided cyclic cleavage - Sci. China-Chem. - 2018 - 2018, 61
31) Gold nanoparticles-based DNA logic gate for miRNA inputs analysis coupling strand displacement reaction and hybridization chain - Part. Part. Syst. Charact. - 2018 - 2018, 35
32) Colorimetric theophylline aggregation assay using an RNA aptamer and non-crosslinking gold nanoparticles - Microchim. Acta - 2018 - 2018, 185
33) A polymyxin B–silver nanoparticle colloidal system and the application of lipopolysaccharide analysis - Analyst - 2018 - 2018, 143
34) An electrochemical approach capable of prostate specific antigen assay in human serum based on exonuclease-aided target recycling - Sens. Actuators, B - 2018 - 2018, 257
35) A highly sensitive gold nanoparticle-based electrochemical aptasensor for theophylline detection - Anal. Chim. Acta - 2018 - 2018, 999
36) Proximity aptasensor for protein detection based on an enzyme-free amplification strategy - Mol. BioSyst. - 2017 - 2017, 13
37) Voltammetric determination of tumor necrosis factor-α based on the use of an aptamer and magnetic nanoparticles loaded with gold nanoparticles - Microchim. Acta - 2017 - 2017, 184
38) Hybridization chain reaction directed DNA superstructures assembly for biosensing applications - Trac-Trends Anal. Chem. - 2017 - 2017, 94
39) Exonuclease and nicking endonuclease-assisted amplified electrochemical detection of coralyne - ChemElectroChem - 2017 - 2017, 4
40) Adamantane derivatives functionalized gold nanoparticles for colorimetric detection of miRNA - Part. Part. Syst. Charact. - 2017 - 2017, 34
41) Enhanced and tunable oxygen carrier and amperometric sensor based on a glassy carbon electrode assembly of a hemoglobin-chitosan-Fe3O4 composite - Microchim. Acta - 2017 - 2017, 184
42) A quartz crystal microbalance sensor for endotoxin assay by monitoring limulus amebocyte lysate protease reaction - Anal. Chim. Acta - 2017 - 2017, 961
43) DNA modified Fe3O4@Au magnetic nanoparticles as selective probes for simultaneous detection of heavy metal ions - ACS Appl. Mater. Interfaces - 2017 - 2017, 9
44) A peptide-based electrochemical biosensor for facile measurement of whole-blood heparin - ChemElectroChem - 2017 - 2017, 4
45) TNF-α responsive DNA star trigon formation from four hairpin probes and the analytical application - Sci. China-Chem. - 2017 - 2017, 60
46) Construction of a specific binding peptide based electrochemical approach for sensitive detection of Zn2+ - J. Electroanal. Chem. - 2016 - 2016, 783
47) Isothermal amplification detection of miRNA based on catalysis of nucleases and voltammetric characteristics of silver nanoparticles - Mol. BioSyst. - 2016 - 2016, 12
48) Identification of glutathione by voltammetric analysis with rolling circle amplification - Anal. Chim. Acta - 2016 - 2016, 943
49) Highly sensitive detection of silver ions enabled by RecJf exonuclease cleavage and reductant mediated electrochemical amplification - ChemElectroChem - 2016 - 2016, 3
50) Near-infrared Ag2S quantum dots-based DNA logic gate platform for miRNA diagnostics - Anal. Chem. - 2016 - 2016, 88
51) DNA tetrahedron and star trigon nanostructures for target recycling detection of nucleic acid - Analyst - 2016 - 2016, 141
52) Peptide and carbon nanotubes assisted detection of apoptosis by square wave voltammetry - Electrochim. Acta - 2016 - 2016, 199
53) Nuclease assisted target recycling and spherical nucleic acids gold nanoparticles recruitment for ultrasensitive detection of microRNA - Electrochim. Acta - 2016 - 2016, 190
54) Apoptosis evaluation by electrochemical techniques - Chem.-Asian J. - 2016 - 2016, 11
55) MicroRNA detection based on analyte triggered nanoparticle localization on a tetrahedral DNA modified electrode followed by hybridization chain reaction dual amplification - Chem. Commun. - 2015 - 2015, 51
56) Identification of cellular microRNA coupling strand displacement polymerization and nicking-endonuclease-based cleavage - ChemPlusChem - 2015 - 2015, 80
57) Study of autocatalytic oxidation reaction of silver nanoparticles and the application for nonenzymatic H2O2 assay - Chem. Phys. Lett. - 2015 - 2015, 635
58) Facile synthesis of carbon nanodots from ethanol and their application in ferric (III) ion assay - J. Mater. Chem. A - 2015 - 2015, 3
59) An elastography analytical method for rapid detection of endotoxin - Analyst - 2015 - 2015, 140
60) Tetrahedral DNA nanostructure-based microRNA biosensor coupled with catalytic recycling of the analyte - ACS Appl. Mater. Interfaces - 2015 - 2015, 7
61) Ultrasensitive detection of microRNA through rolling circle amplification on a DNA tetrahedron decorated electrode - Bioconjug. Chem. - 2015 - 2015, 26
62) Electrochemical tracking hydrogen peroxide secretion in live cells based on autocatalytic oxidation reaction of silver nanoparticles - Electrochem. Commun. - 2015 - 2015, 53
63) Signal amplification by enzymatic tools for nucleic acids - Trac-Trends Anal. Chem. - 2015 - 2015, 67
64) Recent advances in carbon nanodots: synthesis, properties and biomedical applications - Nanoscale - 2015 - 2015, 7
65) Highly sensitive microRNA quantification with zero background signal from silver nanoparticles - Electrochem. Commun. - 2015 - 2015, 51
66) Ultrasensitive electrochemical detection of microRNA with star trigon structure and endonuclease mediated signal amplification - Biosens. Bioelectron. - 2015 - 2015, 63
67) An aptasensor for detection of potassium ions based on RecJf exonuclease mediated signal amplification - Analyst - 2014 - 2014, 139
68) Electrochemical impedance spectroscopy study of proteolysis using unmodified gold nanoparticles - Electrochem. Commun. - 2014 - 2014, 47
69) Peptide-based electrochemical approach for apoptosis evaluation - Biosens. Bioelectron. - 2014 - 2014, 62
70) Gold nanoparticles and cleavage-based dual signal amplification for ultrasensitive detection of silver ions - Anal. Chem. - 2013 - 2013, 85
 
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