Faculty Profile
  TENG Maikun
Department: School of Life Sciences
Mailing Address:
96 Jiazhai Rd, Hefei, Anhui Province
Postal Code:

Research Profile

Maikun Teng,  Professor and Ph.D. supervisor.
At present he holds the position of deputy Dean of School of Life Sciences, USTC. At the same time he also serves as Secretary General of Guiding Committee for Biological Science and Engineering of Ministry of Education, Standing Director for the Chinese Society of Biophysical Society, the Chinese Society of Biochemistry and Molocular Biology and the the Chinese Society of Toxicology, Director for the Committee of Biological Toxin & Toxicology, the Chinese Society of Toxicology.
As a visiting scholar, he once went to Department of Biology, Massachusetts Institute of Technology (October 1986-June 1988), Department of Physiology and Biophysics, University of Illinois, Urbana and Champaign (July 1988 to July 1989), Department of Life Sciences of Purdue University (1992) and Dana-Farber Cancer Institute (August 1996 to November 1997), etc for further study and academic exchange. He has been engaged in teaching and researches in Protein Crystallography and Structural Biology for many years. Currently he is doing research in related protein of gene transcription regulation in eukaryota, sorting and transferring related protein of yeast and toxin protein from snake venom. He once did researches on crystallogphy for DNA-oligonucleotide and DNA-drug complexes, Virus, T-cell receptors and complexes and protein engineering of glucose isomerase, etc.
In recent years he has presided or participated in the research for numerous major research subjects from Ministry of Science and Technology, National Natural Science Foundation of China and Chinese Academy of Science. The “Study on Protein Engineering of Glucose Isomerase” won the Second Prize of Higher Education Award in Science and Technology of Ministry of Education in 2001, and won the First Prize of Scientific and Technological Progress Award of Education Department of Anhui Province in 2000. At present the research subjects he presides and participates in include subjects under the “973 Program”, National Natural Science Foundation of China and Chinese Academy of Sciences. 
Selected Publications
1) Epsin N-terminal homology domains bind on opposite sides of two SNAREs , Proc Natl Acad Sci USA , 2011 , 108 (30):12277-82
2) Structural basis of pre-mRNA recognition by the human cleavage factor Im complex , Cell Research , 2011 , 21(7), 1039-51
3) Structural insights into the down-regulation of Over-expressed p185her2/neu Protein of Transformed Cell by the antibody chA21 , J. Biol. Chem. , 2011 , 286, 31676-83
4) Structural analysis of Rtt106p reveals a DNA-binding role required for heterochromatin silencing , J. Biol. Chem. , 2009 , 285,4251-4262
5) Core Structure of the yeast Spt4-Spt5 Complex: A Conserved Module for Regulation of Transcription Elongation , Structure , 2008 , 16,1649-1658
6) Structure-based de novo prediction of zinc-binding sites in proteins of unknown function , Bioinformatics , 2011 , 27(9), 1262-8
7) Stejnihagin, a novel snake metalloproteinase from Trimeresurus stejnegeri venom, inhibited L-type Ca2+ channels , Toxicon , 2009 , 53,309-315
8) Comparison of protein interaction networks reveals species conservation and divergence , BMC Bioinformatics , 2006 , 7:457
9) Crystal structure of human vacuolar protein sorting protein 29 reveals a phosphodiesterase/nuclease-like fold and two protein-protein interaction sites , J. Biol. Chem., , , 2005 , 280, 22962-22967
10) Crystal structures and amidolytic activities of two glycosylated snake venom serine proteinases , J. Biol. Chem. , 2005 , 280, 10524-10529
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