Faculty Profile
 
  CAI Gang
     
Department: School of Life Sciences
Mailing Address:
No. 443 Huangshan Rd, Hefei, Anhui, PRC 230027
Postal Code:
230037
Phone:
86-551-63603802
Fax:
86-551-63603802
Homepage:
http://cailab.ustc.edu.cn
 
       

Research Profile

	  
      under construction ......
      
 
     
Selected Publications
1) 3.9 Å structure of the yeast Mec1-Ddc2 complex, a homolog of human ATR-ATRIP , Science , 2017 , 2017.12
2) Architecture of the Saccharomyces cerevisiae NuA4/TIP60 complex , Nature Communications , 2018 , 2018
3) Structure of the intact ATM/Tel1 kinase , Nature Communications , 2016 , 2016
4) State-of-The-Art of Single Particle EM. , Acta Biophysica Sinica , (2010) , 26, 560-69
5) Redefining the modular organization of the core Mediator complex , Cell Research , 2014 , 2014.07
6) Architecture of SWI/SNF Chromatin Remodeling Complex , Protein & Cell , 2018 , 2018
7) Structural flexibility and functional interaction of Mediator Cdk8 module(SCI收录) , Protein Cell , 2013 , 4, 911-920
8) AI-2 quorum sensing negatively regulates rbf expression and biofilm formation in Staphylococcus aureus , International Journal of Medical Microbiology , 2017 , 2017.06
9) Crystal and EM structures of human phosphoribosyl pyrophosphate synthase I (PRS1) provide novel insights into the disease-associated mutations , PLos One , 2015 , 2015
10) Crystal structure of DnaT84–153-dT10 ssDNA complex reveals a novel single-stranded DNA binding mode , Nucleic Acids Res , 2014 , 2014
11) Structural basis for receptor recognition and pore formation of a zebrafish aerolysin‐like protein , EMBO Reports , 2016 , 2016
12) Structural investigation of the interaction between the tandem SH3 domains of c-Cbl-associated protein and vinculin , Journal of Structural Biology , 2014 , 2014
13) Architecture of the Mediator head module , Nature , 2011 , 475, 240-3
14) Mediator head module structure and functional interactions. (SCI 收录) , Nat Struct Mol Biol , (2010) , 17, 273-9
15) Interaction of the mediator head module with RNA polymerase II. , Structure , 2012 , 2012
16) Mediator structural conservation and implications for the regulation mechanism (SCI收录) , Structure , (2009) , 17, 559-67
17) A TFIIH-associated mediator head is a basal factor of small nuclear spliced leader RNA gene transcription in early-diverged trypanosomes (SCI收录) , Mol Cell Biol. , (2010) , 30, 5502-13
18) Structure and nucleosome interaction of the yeast NuA4 and Piccolo-NuA4 histone acetyltransferase complexes. , Nat Struct Mol Biol , 2011 , 18, 1196-203
19) Cloning, overexpression, and characterization of a novel thermostable penicillin G acylase from Achromobacter xylosoxidans: probing the molecular basis for its high thermostability. , Appl Environ Microbiol , (2004) , 70, 2764-70
20) Cloning, sequence analysis and expression of the gene encoding a novel wide-spectrum amidase belonging to the amidase signature superfamily from Achromobacter xylosoxidans (SCI收录) , FEMS Microbiol Lett , 2005 , 249, 15-21
 
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