Faculty Profile
 
  ZHAO Gang
     
Department: Department of Electronic Science and Technology
Mailing Address:
Department of Electronic Science and Technology, University of Science and Technology of China, 443 Huangshan Rd, Hefei, Anhui, PR China
Postal Code:
230027
Phone:
Fax:
Homepage:
http://cryobme.ustc.edu.cn/pages/gangZhao.php
 
       

Research Profile

Prof. ZHAO Gang, born in Pei County, Jiangsu Province, in April 1977, received his PhD from University of Science and Technology of China in 2004. He has published over 110 papers on important journals and academic conferences at home and abroad, over 40 of which have been included in SCI and EI.

Work Experience:
4/2011-present: Professor, Department of Electrical Engineering, University of Science and Technology of China
7/2008-10/2010: JSPS Research Fellow, Technical College, Kyushu University
9/2006-4/2011: Associate Professor, Department of Modern Mechanics, University of Science and Technology of China
6/2004-9/2006: Postdoctoral fellow, Department of Modern Mechanics, University of Science and Technology of China

Research Areas:

Cryopreservation of cells and tissues, including: i) explore new approaches to long-term preservation of human blood cells, endothelial cells, stem cells, reproductive cells, arteries and ovarian tissues, etc., in ultralow temperatures; ii) modeling on cryopreservation processes (heat and mass transfer, nucleation and ice growth growth) involved in cryopreservation; etc.

Encapsulation, delivery and slow-releasing technologies for antitumor drugs, including: development of novel microfluidics for physical field sensitive materials synthesis for drug encapsulation, and for on-line synthesis of functional nano-particles for cancer therapy, etc.

Development of novel and high-tech micro- devices, apparatus and equipments, including: i) microfluidics for CPA loading/unloading, ultrafast freezing and thawing, cell encapsulation and vitrification cryopreservation, antitumor drug encapsulation, preparation of functional nanoparticles, etc; ii) integrated microsystems for biopreservation and biotransport, measurement of thermal and mechanical properties, and diagnosis based on micro-cantilever, on-line synthesis of antitumor drugs, etc.

Development of Intelligent medical instruments, including: perfusion-ultrafiltration theory based fully automatic cell and solution treatment instrument, portable artificial kidney system, etc.
 
     
Selected Publications
1) Microfluidics for Cryopreservation , Biotechnology Advances (SCI, IF: 9.848) , 2017.2 , 2017年在线发表
2) Magnetic induction heating of superparamagnetic nanoparticles during rewarming augments the recovery of hUCM-MSCs cryopreserved by vitrification , Acta Biomaterialia (SCI, IF: 6.000) , 2016 , 2016, 33: 264-274
3) Prevention of Osmotic Injury to Human Umbilical Vein Endothelial Cells for Biopreservation: A first step towards biobanking of endothelial cells for vascular tissue engineering , Tissue Eng Part C Methods (SCI, IF: 3.892) , 2016 , 22(3):270-279
4) Vitreous Cryopreservation of Human Umbilical Vein Endothelial Cells with Low Concentration of Cryoprotective Agents for Vascular Tissue Engineering , Tissue Engineering Part C Methods (SCI, IF: 3.892) , 2016 , 22(10), 964-973
5) Nanoparticle-mediated intracellular delivery enables cryopreservation of human adipose-derived stem cells using trehalose as the sole cryoprotectant , ACS Applied Materials & Interfaces , 2015 , 7: 5017-5028
6) Shangquan Wu#, Xiaoli Liu#, Xiarong Zhou, Dayong Gao, Hong Liu*, Gang Zhao*, Qingchuan Zhang* & Xiaoping Wu. Quantification of cell viability and rapid screening anti-cancer drug utilizing nanomechanical fluctuation , Biosensors and Bioelectronics (SCI, IF: 7.476) , 2015 , 2015,77(15):164-173
7) Huang, H., Choi, J.K., Rao W., Zhao S.T., Agarwal P., Gang Zhao, and He, X*. Alginate hydrogel microencapsulation minimizes intracellular ice formation in embryonic stem cells during cryopreservation. , Advanced Functional Materials (SCI, IF: 11.805) , 2015 , 2015
8) Effects of vitrification cryopreservation on follicular morphology and stress relaxation behaviors of human ovarian tissues: sucrose versus trehalose as the non-permeable protective agent.(SCI, IF: 4.585) , Hum. Reprod. , 2015 , 2015, 30(4): 877-883
9) High accuracy thermal conductivity determination of semi-regid biological tissues and aqueous cryoprotective agents using a microfabricated thermal sensor (SCI, IF: 5.078) , Scientific Reports , 2015 , 2015,5:10377
10) Wu, P., J. Yi, G. Zhao*, Z. Huang, B. Qiu and D. Gao. Active contour-based cell segmentation during freezing and its application in cryopreservation. IEEE Trans Biomed Eng, 2015, 62(1): 284-295. (SCI, IF 2.233) , IEEE Trans Biomed Eng , 2015 , 62(1)
11) Yunpeng Xu, Gang Zhao*, Xiaoming Zhou, Weiping Ding, Zhiquan Shu, Dayong Gao. Evaluation of biotransport phenomena in freezing human embryonic kidney cells (HEK293T) (SCI, IF 2.137) , Cryobiology , 2014 , 68(2):294–302
12) Tao Wang, Gang Zhao*, Xin M. Liang, Yunpeng Xu, Yang Li, Heyu Tang, Rui Jiang, Dayong Gao. Effect of Superparamagnetic Nanoparticles on Microwave Rewarming of Cryopreserved Tissues.(SCI, IF 2.137) , Cryobiology , 2014 , 68(2): 234–243
13) Gang Zhao*, Hiroshi Takamatsu, Xiaoming He, et al. The effect of solution nonideality on modeling transmembrane water transport and diffusion-limited intracellular ice formation during cryopreservation. DOI: 10.1063/1.4870826 , Journal of Applied Physics , 2014 , 115
14) Augmented cancer destruction by nanodrug surface-decorated with chitosan to target CD44+ cancer cells , ACS Nano , 2015 , 9(6): 5725-5740
15) Nanotopograghical Surfaces for Stem Cell Fate Control: Engineering Mechanobiology from the Bottom , Nano Today , 2014 , 9: 759-784
16) G. Zhao*, H. F. Zhang, X. J. Guo, D. W. Luo, and D. Y. Gao, "Effect of blood flow and metabolism on multidimensional heat transfer during cryosurgery" , Medical Engineering & Physics , 2007 , 29:205-215
17) G. Zhao*, D. W. Luo, and D. Y. Gao, "Universal model for intracellular ice formation and its growth" , AIChE Journal , 2006 , 52:2596-2606
 
Recruitment information
Email: ZhaoG@ustc.edu.cn
       
       
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