Faculty Profile
 
  Cui Hua
     
Department: Department of Chemistry
Mailing Address:
96 Jinzai Road, Hefei, Anhui
Postal Code:
230026
Phone:
86-551-63600730
Fax:
86-551-63600730
Homepage:
http://cl.ustc.edu.cn
 
       

Research Profile

Dr Hua Cui received her Ph.D. from University of Science and Technology of China in 1990. She was appointed as a lecturer in 1990, as an associate professor in 1995 and as a professor & head in 2000 in Analytical Division, Department of Chemistry, University of Science & Technology of China. During the time, she also conducted some research work as a postdoctoral at Department of Pharmaceutical Analysis, Faculty of Pharmacy, Utrecht University and as a visiting scholars at Department of Biology, Jackson State University.

Research interests are chemiluminescence (CL) and electrochemiluminescence (ECL) and their applications to immunoassays and nucleic acid analysis in the fields such as public health, food safety, environmental monitoring and so on. Current work focuses on the investigation of metal nanoparticle - initiated CL/ECL systems, the development of novel luminescence functionalized nanoprobes, signal amplification strategies and methodologies for ultrasensitive CL and ECL bioassays and their applications to early diagnosis and treatment of life-threatening diseases (such as tuberculosis, acute myocardial infarction, and cancer etc.), and assessment of food safety.

Selected Honors:

The K. C. Wong Education Foundation Award for Teaching, The First Prize, 2009
Award for 3nd Ten Outstanding Women Award Nominations, The Chinese Academy of Science, 2009
Award for The National Science Fund for Distinguished Young Scholars, The National Natural Science Foundation of China, 2006 
Award for The Hundred Talent Program, The Chinese Academy of Sciences, 2000 
 
     
Selected Publications
1) A Homogeneous Signal-On Strategy for the Detection of rpoB Genes of Mycobacterium tuberculosis Based on Electrochemiluminescent Graphene Oxide and Ferrocene Quenching , Anal. Chem , 2014 , 2014, 86 (3), 1608–1613
2) Gold Nanoparticles Bifunctionalized by Chemiluminescence Reagent and Catalyst Metal Complexes: Synthesis and Unique Chemiluminescence Property , Anal. Chem. , 2014 , 2014, 86 (6), 2857–2861.
3) A General Chemiluminescence Strategy for Measuring Aptamer–Target Binding and Target Concentration , Anal. Chem , 2014 , 2014, 86 (11), 5559–5566.
4) Molecular Encoder - Decoder Based on Assembly of Graphene with Dye-labeled DNA , Chem. Commun. , 2014 , 2014,50, 7994-7997.
5) High-density assembly of chemiluminescence functionalized gold nanodots on multiwalled carbon nanotubes and their application as biosensing platforms , Nanoscale , 2014 , 2014, 6(5), 2563 - 2566.
6) A general strategy to prepare homogeneous and reagentless GO/lucigenin&enzyme biosensors for detection of small biomolecules , Biosens. Bioelectron. , 2014 , 2014, 57, 65-70.
7) A competitive immunoassay for sensitive detection of small moleculeschloramphenicol based on luminol functionalized silver nanoprobe , Anal. Chim. Acta , 2014 , 2014, 812, 236-242.
8) Electrochemiluminescence bioassay for thrombin based on dynamic assembly of aptamer, thrombin and N-(aminobutyl)-N-(ethylisoluminol) functionalized gold nanoparticles , Electrochimica Acta , 2014 , 2014, 125, 156–162.
9) A label-free electrochemiluminescence aptasensor for thrombin based on novel assembly strategy of oligonucleotide and luminol functionalized gold nanoparticles , Biosens. Bioelectron. , 2013 , 2013, 39, 261-267.
10) A novel homogeneous label-free aptasensor for 2,4,6-trinitrotoluene detection based on an assembly strategy of electrochemiluminescent graphene oxide with gold nanoparticles and aptamer , Biosens. Bioelectron. , 2013 , 2013, 43. 137–142.
11) Highly chemiluminescent gold nanopopcorns functionalized by N-(aminobutyl)-N-(ethylisoluminol) with lipoic acid as a co-stabilizing reagent , J. Mater. Chem. B , 2013 , 2013, 1, 970-977
12) Label free and homogeneous histone sensing based on chemiluminescence resonance energy transfer between lucigenin and gold nanoparticles , Biosens. Bioelectron. , 2013 , 2013, (47), 313-317
13) Preparation and electrochemiluminescent and photoluminescent properties of a graphene oxide colloid , Carbon , 2013 , 2013,(56),201-207
14) A homogeneous hemin/G-quadruplex DNAzyme based turn-on chemiluminescence aptasensor for interferon-gamma detection via in-situ assembly of luminol functionalized gold nanoparticles, deoxyribonucleic acid, interferon-gamma and hemin , Anal. Chim. Acta , 2013 , 2013, 60-64
15) N-(Aminobutyl)-N-(ethylisoluminol) and hemin dual-functionalized graphene hybrids with high chemiluminescence , Chem. Commun. , 2013 , 2013, 49, 9794-9796
16) Quenching the Chemiluminescence of Acridinium Ester by Graphene Oxide for Label-Free and Homogeneous DNA Detection , ACS Appl. Mater. Interfaces , 2013 , 2013, 5 (21), pp 11336–11340
17) Chemiluminescent Logic Gates Based on Functionalized Gold Nanoparticles/Graphene Oxide Nanocomposites , Chemistry - A European Journal , 2013 , 2013, 19(40), 13584–13589.
18) A graphene-based composite material noncovalently functionalized with a chemiluminescence reagent: synthesis and intrinsic chemiluminescence activity , Chem. Commun , 2012 , 2012, 48, 2894-2896.
19) Synthesis of highly chemiluminescent graphene oxide/silver nanoparticle nano-composites and their analytical applications , J. Mater. Chem , 2012 , 2012, 22, 9086-9091
20) Electrochemiluminescence biosensor for the assay of small molecule and protein based on bifunctional aptamer and chemiluminescent functionalized gold nanoparticles , Anal. Chim. Acta, , 2012 , 2012, 715, 86-92.
21) Synthesis of Dendritic Platinum Nanoparticles/Lucigenin/Reduced Graphene Oxide Hybrid with Chemiluminescence Activity , Chem. Eur. J., , 2012 , 2012, 18, 4823-4826.
22) Synthesis of electrochemiluminescent graphene oxide functionalized with a ruthenium(II) complex and its use in the detection of tripropylamine , Carbon, , 2012 , 2012, 50, 2539-2545.
23) Amino acids as the source for producing carbon nanodots: microwave assisted one-step synthesis, intrinsic photoluminescence property and intense chemiluminescence enhancement , Chem. Commun., , 2012 , 2012, 48, 9634-9636
24) Fabrication of Luminol and Lucigenin Bifunctionalized Gold Nnanoparticles/Graphene Oxide Nanocomposites with Dual-Wavelength Chemiluminescence , J. Phys. Chem. C, , 2012 , 2012, 116, 12953-12957.
25) Synthesis of N-(aminobutyl)-N-(ethylisoluminol) functionalized gold nanomaterials for chemiluminescent bio-probe , Chem. Commun. , 2011 , 47, 4959-4961.
26) Nanoparticle-based electrochemiluminescence immunosensor with enhanced sensitivity for cardiac troponin I using N-(aminobutyl)-N-(ethylisoluminol)-functionalized gold nanoparticles as labels , Biosens. Bioelectron , 2011 , 2011, 27, 18-24
27) Ultrasensitive electrochemiluminescence immunosensor based on luminol functionalized gold nanoparticle labeling , Biosens. Bioelectron. , 2010 , 25, 2290-2295.
28) pH-dependent catalytic properties of Pd-Ag nanoparticles in luminol chemiluminescence , Chem. Commun. , 2010 , 46, 1520-1522.
29) A novel electrochemiluminescence strategy for ultrasensitive DNA assay using luminol functionalized gold nanoparticles multi-labeling and amplification of gold nanoparticles and biotin-streptavidin system , Chem. Commun. , 2010 , 46, 7560-7562.
30) Time-tunable autocatalytic lucigenin chemiluminescence initiated by platinum nanoparticles and ethanol , Chem. Commun. , 2009 , 18, 2574-2576.
31) Growth mechanism of flowerlike gold nanostructures: Surface Plasmon Resonance (SPR) and Resonance Rayleigh Scattering (RRS) approaches to growth monitoring , J. Phys. Chem. C , 2008 , 112, 16348-16353.
32) Synthesis, characterization, and electrochemiluminescence of luminol-reduced gold nanoparticles and their application in a hydrogen peroxide sensor , Chem. Eur. J. , 2007 , 13, 6975-6984.
33) Light emission of gold nanoparticles induced by the reaction of bis(2,4,6-trichlorophenyl) oxalate and hydrogen peroxide , Anal. Chem. , 2005 , 77 (19), 6402-6406
34) Gold nanoparticle-catalyzed luminol chemiluminescence and its analytical applications , Anal. Chem. , 2005 , 77 (10), 3324-3329
35) Multi-channel electrochemiluminescence of luminol in neutral and alkaline aqueous solutions on a gold nanoparticles self-assembled electrode , Anal. Chem. , 2004 , 76, 4002-4010
 
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TEL: +86-551-63600279, E-mail: tianlin@ustc.edu.cn