Faculty Profile
 
  WU Jihui
     
Department: School of Life Science
Mailing Address:
school of life sciences, University of Science and Technology of China, 443 Huangshan Rd, Hefei, Anhui, PR China
Postal Code:
230026
Phone:
+86-551-63600394
Fax:
+86-551-63600374
Homepage:
http://biox.ustc.edu.cn/szdw/szjs/201006/t20100630_23178.html
 
       

Research Profile

    Professor and PhD. supervisor.
BSc (1982)in Cytobiology from University of Science and Technology of China and MSc (1988)from Institute of Physics, Chinese Academy of Sciences.
From January 1995 to January 1996, he studied NMR experiment techniques and correction methods for protein structure at Swiss Federal Institute of Polymer Biology & Biophysics, Zurich.
From October 10 to August 1985, he was working in Wuhan Institute of Virology, Chinese Academy of Sciences, and engaged in the study on ds-RNA of rotavirus, preservation of plant viruses, etc. Since October 1988, he has taught at the School of Life Sciences, USTC and been engaged in the research work on NMR and structural biology.
 
     
Selected Publications
1) Recognition of Unmodified Histone H3 by the First PHD Finger of Bromodomain-PHD Finger Protein 2 Provides Insights into the Regulation of Histone Acetyltransferases Monocytic Leukemic Zinc-finger Protein (MOZ) and MOZ-related factor (MORF) , Journal of Biological Chemistry , 2011 , (2011)286,36944-36955
2) Sparsely sampled high-resolution 4-D experiments for efficient backbone resonance assignment of disordered proteins , Journal of Magnetic Resonance , 2011 , (2011) 209,94-100
3) A Large Intrinsically Disordered Region in SKIP and its Disorder-Order Transition Induced by PPIL1 Binding Revealed by NMR , J Biol Chem , 2010 , (2010)285:4951-4963
4) Conformational change upon ligand binding and dynamics of the PDZ domain from Leukemia-associated Rho guanine nucleotide exchange factor , Protein Science , 2008 , (2008)17:1003-1014
5) Interesting Structural and Dynamical Behaviors Exhibited by the AF-6 PDZ Domain upon Bcr Peptide Binding. , Biochemistry , 2007 , (2007) 46 (51):15042 -15053
6) Solution structure of AF-6 PDZ domain and its interaction with the C-terminal peptides from neurexin and Bcr , J Biol Chem. , 2005 , 280(14):13841-13847
 
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