Faculty Profile
 
  Na Zhang
     
Department: High Magnetic Field Laboratory, Chinese Academy of Sciences in Hefei
Mailing Address:
High Magnetic Field Laboratory, Chinese Academy of Sciences, Shu Shan Hu Lu 350, Hefei, Anhui 230031 P.R.China
Postal Code:
230031
Phone:
86-551-65591582
Fax:
Homepage:
http://sourcedb.hf.cas.cn/rjc/ch/201601/t20160119_4520113.html
 
       

Research Profile

	  
      under construction ......
      
 
     
Selected Publications
1) (3+1) assembly of three human telomeric DNA repeats into an asymmetrical dimeric G-quadruplex. , J Am Chem Soc. , 2005 , (2005) 127, p17277-17285.
2) Activated ribonucleotides undergo a sugar pucker switch upon binding to a single-stranded RNA template , J Am Chem Soc. , 2012 , (2012) 134, p3691-3694.
3) Synthesis of N3′-P5′-linked Phosphoramidate DNA by Nonenzymatic Template-Directed Primer Extension , J Am Chem Soc. , 2013 , (2013), 135, p924-932.
4) Evolution of functional nucleic acids in the presence of nonheritable backbone heterogeneity , Proc Natl Acad Sci USA , 2011 , (2011) 108, p13492-13497.
5) Thermodynamic profiles and nuclear magnetic resonance studies of oligonucleotide duplexes containing single diastereomeric spiroiminodihydantoin lesions. , Biochemistry. , 2013 , (2013) 52, p1354-1363.
6)  NMR and computational studies of stereoisomeric equine estrogen-derived DNA cytidine adducts in oligonucleotide duplexes: opposite orientations of diastereomeric forms. , Biochemistry , 2009 , (2009) 48, p7098-7109.
7)  Solution structure of a designed spirocyclic helical ligand binding at a two-base bulge site in DNA. , Biochemistry , 2007 , (2007) 46, p4793-4803.
8) Spirocyclic helical compounds as binding agents for bulged RNA, including HIV-2 TAR, , Chem. Commun. , 2006 , (2006) 42, p4431-4433.
 
Recruitment information
Postdoc/PhD student/MS student positions are available. Postdocs, Ph.D and MS graduate students with strong background in biology, chemistry are very welcome, especially with hand-on experiences in macromolecular NMR, structural biology and/or RNA/DNA biology are highly preferred. If interested, please send your CV to nazhang@hmfl.cas.cn
       
       
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TEL: +86-551-63600279, E-mail: tianlin@ustc.edu.cn